Section one: Contracting authority/entity
one.1) Name and addresses
University of Dundee
Procurement, 3rd Floor, Tower Building, Nethergate
Dundee
DD1 4HN
Contact
Mary Kirkpatrick
Telephone
+44 1382386604
Country
United Kingdom
NUTS code
UKM71 - Angus and Dundee City
Internet address(es)
Main address
Buyer's address
https://www.publiccontractsscotland.gov.uk/search/Search_AuthProfile.aspx?ID=AA00105
Section two: Object
two.1) Scope of the procurement
two.1.1) Title
Term Framework for the Provision of Chemistry Synthesis and other Chemistry Services Outsourcing Framework
Reference number
UoD-LAB031-TC-2023
two.1.2) Main CPV code
- 73110000 - Research services
two.1.3) Type of contract
Services
two.1.4) Short description
Second-Generation Framework for the provision of Chemistry Synthesis and other Chemistry Services Outsourcing with initial term of two (2) years with the option to extend for up to 2 x 12 months, if required, at the sole discretion of the University and subject to ongoing satisfactory performance by the appointed Service Providers.
The Services will include:
1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;
2.Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;
3. Scale up of chemistry, up to 200g;
4.Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.
5.Synthesis of intermediates at 5-100g;
For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;
6. Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.
Section six. Complementary information
six.6) Original notice reference
Notice number: 2024/S 000-009350
Section seven. Changes
seven.1) Information to be changed or added
seven.1.2) Text to be corrected in the original notice
Section number
IV.2.2
Place of text to be modified
Time limit
Instead of
Date
3 May 2024
Local time
5:00pm
Read
Date
13 May 2024
Local time
5:00pm
Section number
IV.2.6
Place of text to be modified
Minimum time frame during which the tenderer must maintain the tender
Instead of
Date
28 June 2024
Read
Date
12 July 2024
Section number
IV.2.7
Place of text to be modified
Conditions for opening of tenders
Instead of
Date
3 May 2024
Local time
5:00pm
Read
Date
13 May 2024
Local time
12:00pm
seven.2) Other additional information
Request for extension from potential tenderers.