Section one: Contracting authority
one.1) Name and addresses
NHS England
7&8 Wellington Place
Leeds
LS1 4AP
Contact
Anna Salt
Country
United Kingdom
Region code
UKE - Yorkshire and the Humber
Internet address(es)
Main address
Buyer's address
one.4) Type of the contracting authority
Body governed by public law
one.5) Main activity
Health
Section two: Object
two.1) Scope of the procurement
two.1.1) Title
NHS Genomic Medicine Service - Most Suitable Provider Process
Reference number
C368833
two.1.2) Main CPV code
- 85100000 - Health services
two.1.3) Type of contract
Services
two.1.4) Short description
This is a notice of intention to make an award in respect of the NHS Genomic Medicine Service pursuant to the Most Suitable Provider (MSP) Process for the NHS Genomic Medicine Service (NHS GMS). For the avoidance of doubt, this is an intention to award notice. A notice of the confirmation of the award of each contract will be issued once they are signed.
Pursuant to the NHS GMS contracts, provider are to provide the following functions:
• Organisational leadership, governance and partnership arrangements;
• Delivery of genomic testing outlined in the National Genomic Test Directory (NGTD);
• Laboratory operating model;
• Clinical function: cancer genomics;
• Clinical function: rare disease;
• Clinical function: population health;
• Promotion of and supporting and leading where relevant science, research and / or innovation;
• Transformation and Service Improvement;
• People – workforce, education and training; and
• Data and digital
two.1.6) Information about lots
This contract is divided into lots: Yes
two.1.7) Total value of the procurement (excluding VAT)
Value excluding VAT: £5,175,000,000
two.2) Description
two.2.1) Title
Lot 1 – NHS North-West GMS
Lot No
1
two.2.2) Additional CPV code(s)
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKD - North West (England)
two.2.4) Description of the procurement
Pursuant to the NHS GMS contracts, providers are to provide the following functions:
* Organisational leadership, governance and partnership arrangements;
* Delivery of genomic testing outlined in the National Genomic Test Directory (NGTD);
* Laboratory operating model;
* Clinical function: cancer genomics;
* Clinical function: rare disease;
* Clinical function: population health;
* Promotion of and supporting and leading where relevant science, research and / or innovation;
* Transformation and Service Improvement;
* People – workforce, education and training; and
* Data and digital
The Commissioner intends to award contracts following the Most Suitable Process to 7 providers which are existing providers. This is an expansion of existing services which, under PSR, constitutes a new service.
The approximate lifetime value of the contract for all Lots is £5,175,000,000.
The services will start on 1st April 2026 and the initial period will run until 31st March 3034 with an option to extend for up to a further 2 years (of 2 x 12 month periods).
Please note that the figure included in the 'Awarded Value' section of this part of the notice is the total approximate lifetime value of all Lots of the NHS Genomic Medicine Service contract. For the avoidance of doubt, this is not the approximate lifetime value for each Lot. The approximate lifetime value for each Lot shall be included within the confirmation of contract award notice (which shall be issued once contracts have been signed).
two.2.5) Award criteria
Cost criterion - Name: Most suitable provider process with regard to the key Criteria / Weighting: 100
two.2.11) Information about options
Options: Yes
Description of options
Options to extend for up to a further 2 years (of 2 x 12 month periods) following the initial 8 year contract period.
two.2.13) Information about European Union Funds
The procurement is related to a project and/or programme financed by European Union funds: No
two.2) Description
two.2.1) Title
Lot 2 – NHS North-East and Yorkshire GMS
Lot No
2
two.2.2) Additional CPV code(s)
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKC - North East (England)
two.2.4) Description of the procurement
Pursuant to the NHS GMS contracts, providers are to provide the following functions:
* Organisational leadership, governance and partnership arrangements;
* Delivery of genomic testing outlined in the National Genomic Test Directory (NGTD);
* Laboratory operating model;
* Clinical function: cancer genomics;
* Clinical function: rare disease;
* Clinical function: population health;
* Promotion of and supporting and leading where relevant science, research and / or innovation;
* Transformation and Service Improvement;
* People – workforce, education and training; and
* Data and digital
The Commissioner intends to award contracts following the Most Suitable Process to 7 providers which are existing providers. This is an expansion of existing services which, under PSR, constitutes a new service.
The approximate lifetime value of the contract for all Lots is £5,175,000,000.
The services will start on 1st April 2026 and the initial period will run until 31st March 3034 with an option to extend for up to a further 2 years (of 2 x 12 month periods).
Please note that the figure included in the 'Awarded Value' section of this part of the notice is the total approximate lifetime value of all Lots of the NHS Genomic Medicine Service contract. For the avoidance of doubt, this is not the approximate lifetime value for each Lot. The approximate lifetime value for each Lot shall be included within the confirmation of contract award notice (which shall be issued once contracts have been signed).
two.2.5) Award criteria
Cost criterion - Name: Most suitable provider process with regard to the key Criteria / Weighting: 100
two.2.11) Information about options
Options: Yes
Description of options
Option to extend for up to a further 2 years (of 2 x 12 month periods) following the initial 8 year contract period
two.2.13) Information about European Union Funds
The procurement is related to a project and/or programme financed by European Union funds: No
two.2) Description
two.2.1) Title
Lot 3 – NHS Central and South GMS
Lot No
3
two.2.2) Additional CPV code(s)
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKG - West Midlands (England)
two.2.4) Description of the procurement
Pursuant to the NHS GMS contracts, providers are to provide the following functions:
* Organisational leadership, governance and partnership arrangements;
* Delivery of genomic testing outlined in the National Genomic Test Directory (NGTD);
* Laboratory operating model;
* Clinical function: cancer genomics;
* Clinical function: rare disease;
* Clinical function: population health;
* Promotion of and supporting and leading where relevant science, research and / or innovation;
* Transformation and Service Improvement;
* People – workforce, education and training; and
* Data and digital
The Commissioner intends to award contracts following the Most Suitable Process to 7 providers which are existing providers. This is an expansion of existing services which, under PSR, constitutes a new service.
The approximate lifetime value of the contract for all Lots is £5,175,000,000.
The services will start on 1st April 2026 and the initial period will run until 31st March 3034 with an option to extend for up to a further 2 years (of 2 x 12 month periods).
Please note that the figure included in the 'Awarded Value' section of this part of the notice is the total approximate lifetime value of all Lots of the NHS Genomic Medicine Service contract. For the avoidance of doubt, this is not the approximate lifetime value for each Lot. The approximate lifetime value for each Lot shall be included within the confirmation of contract award notice (which shall be issued once contracts have been signed).
two.2.5) Award criteria
Cost criterion - Name: Most suitable provider process with regard to the key Criteria / Weighting: 100
two.2.11) Information about options
Options: Yes
Description of options
Option to extend for up to a further 2 years (of 2 x 12 month periods) following the initial 8 year contract period
two.2.13) Information about European Union Funds
The procurement is related to a project and/or programme financed by European Union funds: No
two.2) Description
two.2.1) Title
Lot 4 – NHS East GMS
Lot No
4
two.2.2) Additional CPV code(s)
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKH - East of England
two.2.4) Description of the procurement
Pursuant to the NHS GMS contracts, providers are to provide the following functions:
* Organisational leadership, governance and partnership arrangements;
* Delivery of genomic testing outlined in the National Genomic Test Directory (NGTD);
* Laboratory operating model;
* Clinical function: cancer genomics;
* Clinical function: rare disease;
* Clinical function: population health;
* Promotion of and supporting and leading where relevant science, research and / or innovation;
* Transformation and Service Improvement;
* People – workforce, education and training; and
* Data and digital
The Commissioner intends to award contracts following the Most Suitable Process to 7 providers which are existing providers. This is an expansion of existing services which, under PSR, constitutes a new service.
The approximate lifetime value of the contract for all Lots is £5,175,000,000.
The services will start on 1st April 2026 and the initial period will run until 31st March 3034 with an option to extend for up to a further 2 years (of 2 x 12 month periods).
Please note that the figure included in the 'Awarded Value' section of this part of the notice is the total approximate lifetime value of all Lots of the NHS Genomic Medicine Service contract. For the avoidance of doubt, this is not the approximate lifetime value for each Lot. The approximate lifetime value for each Lot shall be included within the confirmation of contract award notice (which shall be issued once contracts have been signed).
two.2.5) Award criteria
Cost criterion - Name: Most suitable provider process with regard to the key Criteria / Weighting: 100
two.2.11) Information about options
Options: Yes
Description of options
Option to extend for up to a further 2 years (of 2 x 12 month periods) following the initial 8 year contract period
two.2.13) Information about European Union Funds
The procurement is related to a project and/or programme financed by European Union funds: No
two.2) Description
two.2.1) Title
Lot 5 – NHS South-West GMS
Lot No
5
two.2.2) Additional CPV code(s)
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKK - South West (England)
two.2.4) Description of the procurement
Pursuant to the NHS GMS contracts, providers are to provide the following functions:
* Organisational leadership, governance and partnership arrangements;
* Delivery of genomic testing outlined in the National Genomic Test Directory (NGTD);
* Laboratory operating model;
* Clinical function: cancer genomics;
* Clinical function: rare disease;
* Clinical function: population health;
* Promotion of and supporting and leading where relevant science, research and / or innovation;
* Transformation and Service Improvement;
* People – workforce, education and training; and
* Data and digital
The Commissioner intends to award contracts following the Most Suitable Process to 7 providers which are existing providers. This is an expansion of existing services which, under PSR, constitutes a new service.
The approximate lifetime value of the contract for all Lots is £5,175,000,000.
The services will start on 1st April 2026 and the initial period will run until 31st March 3034 with an option to extend for up to a further 2 years (of 2 x 12 month periods).
Please note that the figure included in the 'Awarded Value' section of this part of the notice is the total approximate lifetime value of all Lots of the NHS Genomic Medicine Service contract. For the avoidance of doubt, this is not the approximate lifetime value for each Lot. The approximate lifetime value for each Lot shall be included within the confirmation of contract award notice (which shall be issued once contracts have been signed).
two.2.5) Award criteria
Cost criterion - Name: Most suitable provider process with regard to the key Criteria / Weighting: 100
two.2.11) Information about options
Options: Yes
Description of options
Option to extend for up to a further 2 years (of 2 x 12 month periods) following the initial 8 year contract period
two.2.13) Information about European Union Funds
The procurement is related to a project and/or programme financed by European Union funds: No
two.2) Description
two.2.1) Title
Lot 6 – NHS North Thames GMS
Lot No
6
two.2.2) Additional CPV code(s)
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKI - London
two.2.4) Description of the procurement
Pursuant to the NHS GMS contracts, providers are to provide the following functions:
* Organisational leadership, governance and partnership arrangements;
* Delivery of genomic testing outlined in the National Genomic Test Directory (NGTD);
* Laboratory operating model;
* Clinical function: cancer genomics;
* Clinical function: rare disease;
* Clinical function: population health;
* Promotion of and supporting and leading where relevant science, research and / or innovation;
* Transformation and Service Improvement;
* People – workforce, education and training; and
* Data and digital
The Commissioner intends to award contracts following the Most Suitable Process to 7 providers which are existing providers. This is an expansion of existing services which, under PSR, constitutes a new service.
The approximate lifetime value of the contract for all Lots is £5,175,000,000.
The services will start on 1st April 2026 and the initial period will run until 31st March 3034 with an option to extend for up to a further 2 years (of 2 x 12 month periods).
Please note that the figure included in the 'Awarded Value' section of this part of the notice is the total approximate lifetime value of all Lots of the NHS Genomic Medicine Service contract. For the avoidance of doubt, this is not the approximate lifetime value for each Lot. The approximate lifetime value for each Lot shall be included within the confirmation of contract award notice (which shall be issued once contracts have been signed).
two.2.5) Award criteria
Cost criterion - Name: Most suitable provider process with regard to the key Criteria / Weighting: 100
two.2.11) Information about options
Options: Yes
Description of options
Option to extend for up to a further 2 years (of 2 x 12 month periods) following the initial 8 year contract period
two.2.13) Information about European Union Funds
The procurement is related to a project and/or programme financed by European Union funds: No
two.2) Description
two.2.1) Title
Lot 7 – NHS South-East GMS
Lot No
7
two.2.2) Additional CPV code(s)
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKJ - South East (England)
two.2.4) Description of the procurement
Pursuant to the NHS GMS contracts, providers are to provide the following functions:
* Organisational leadership, governance and partnership arrangements;
* Delivery of genomic testing outlined in the National Genomic Test Directory (NGTD);
* Laboratory operating model;
* Clinical function: cancer genomics;
* Clinical function: rare disease;
* Clinical function: population health;
* Promotion of and supporting and leading where relevant science, research and / or innovation;
* Transformation and Service Improvement;
* People – workforce, education and training; and
* Data and digital
The Commissioner intends to award contracts following the Most Suitable Process to 7 providers which are existing providers. This is an expansion of existing services which, under PSR, constitutes a new service.
The approximate lifetime value of the contract for all Lots is £5,175,000,000.
The services will start on 1st April 2026 and the initial period will run until 31st March 3034 with an option to extend for up to a further 2 years (of 2 x 12 month periods).
Please note that the figure included in the 'Awarded Value' section of this part of the notice is the total approximate lifetime value of all Lots of the NHS Genomic Medicine Service contract. For the avoidance of doubt, this is not the approximate lifetime value for each Lot. The approximate lifetime value for each Lot shall be included within the confirmation of contract award notice (which shall be issued once contracts have been signed).
two.2.5) Award criteria
Cost criterion - Name: Most suitable provider process with regard to the key Criteria / Weighting: 100
two.2.11) Information about options
Options: Yes
Description of options
Option to extend for up to a further 2 years (of 2 x 12 month periods) following the initial 8 year contract period
two.2.13) Information about European Union Funds
The procurement is related to a project and/or programme financed by European Union funds: No
Section four. Procedure
four.1) Description
four.1.1) Type of procedure
Award of a contract without prior publication of a call for competition in the cases listed below
- The procurement falls outside the scope of application of the regulations
Explanation:
This is a Provider Selection Regime (PSR) intention to award notice. The awarding of this contract is subject to the Health Care Services (Provider Selection Regime) Regulations 2023. For the avoidance of doubt, the provisions of the Procurement Act Regulations 2023 do not apply to this award. The standstill period begins on the day after the publication of this notice. Representations by providers must be made to decision makers by Tuesday 4th November 2025. This contract has not yet formally been awarded; this notice serves as an intention to award under the PSR.
four.1.8) Information about the Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement: No
four.2) Administrative information
four.2.1) Previous publication concerning this procedure
Notice number: 2025/S 000-042969
Section five. Award of contract
Lot No
1
Title
Lot 1 - NHS North-West GMS
A contract/lot is awarded: Yes
five.2) Award of contract
five.2.1) Date of conclusion of the contract
21 October 2025
five.2.2) Information about tenders
Number of tenders received: 3
The contract has been awarded to a group of economic operators: No
five.2.3) Name and address of the contractor
Manchester University NHS Foundation Trust
Manchester
Country
United Kingdom
NUTS code
- UKD3 - Greater Manchester
The contractor is an SME
No
five.2.4) Information on value of contract/lot (excluding VAT)
Total value of the contract/lot: £5,175,000,000
Section five. Award of contract
Lot No
2
Title
Lot 2 - NHS North-East and Yorkshire GMS
A contract/lot is awarded: Yes
five.2) Award of contract
five.2.1) Date of conclusion of the contract
21 October 2025
five.2.2) Information about tenders
Number of tenders received: 3
The contract has been awarded to a group of economic operators: No
five.2.3) Name and address of the contractor
The Newcastle upon Tyne Hospitals NHS Foundation Trust
Newcastle
Country
United Kingdom
NUTS code
- UKC2 - Northumberland and Tyne and Wear
The contractor is an SME
No
five.2.4) Information on value of contract/lot (excluding VAT)
Total value of the contract/lot: £5,175,000,000
Section five. Award of contract
Lot No
3
Title
Lot 3 NHS Central and South GMS
A contract/lot is awarded: Yes
five.2) Award of contract
five.2.1) Date of conclusion of the contract
21 October 2025
five.2.2) Information about tenders
Number of tenders received: 3
The contract has been awarded to a group of economic operators: No
five.2.3) Name and address of the contractor
Birmingham Women’s and Children’s NHS Foundation Trust
Birmingham
Country
United Kingdom
NUTS code
- UKG3 - West Midlands
The contractor is an SME
No
five.2.4) Information on value of contract/lot (excluding VAT)
Total value of the contract/lot: £5,175,000,000
Section five. Award of contract
Lot No
4
Title
Lot 4 NHS East GMS
A contract/lot is awarded: Yes
five.2) Award of contract
five.2.1) Date of conclusion of the contract
21 October 2025
five.2.2) Information about tenders
Number of tenders received: 3
The contract has been awarded to a group of economic operators: No
five.2.3) Name and address of the contractor
Cambridge University Hospitals NHS Foundation Trust
Cambridge
Country
United Kingdom
NUTS code
- UKH1 - East Anglia
The contractor is an SME
No
five.2.4) Information on value of contract/lot (excluding VAT)
Total value of the contract/lot: £5,175,000,000
Section five. Award of contract
Lot No
5
Title
Lot 5 NHS South-West GMS
A contract/lot is awarded: Yes
five.2) Award of contract
five.2.1) Date of conclusion of the contract
21 October 2025
five.2.2) Information about tenders
Number of tenders received: 3
The contract has been awarded to a group of economic operators: No
five.2.3) Name and address of the contractor
North Bristol NHS Trust
Bristol
Country
United Kingdom
NUTS code
- UKK1 - Gloucestershire, Wiltshire and Bristol/Bath area
The contractor is an SME
No
five.2.4) Information on value of contract/lot (excluding VAT)
Total value of the contract/lot: £5,175,000,000
Section five. Award of contract
Lot No
6
Title
Lot 6 NHS North Thames GMS
A contract/lot is awarded: Yes
five.2) Award of contract
five.2.1) Date of conclusion of the contract
21 October 2025
five.2.2) Information about tenders
Number of tenders received: 3
The contract has been awarded to a group of economic operators: No
five.2.3) Name and address of the contractor
Great Ormond Street Hospital for Children NHS Foundation Trust
London
Country
United Kingdom
NUTS code
- UKI3 - Inner London – West
The contractor is an SME
No
five.2.4) Information on value of contract/lot (excluding VAT)
Total value of the contract/lot: £5,175,000,000
Section five. Award of contract
Lot No
7
Title
Lot 7 NHS South-East GMS
A contract/lot is awarded: Yes
five.2) Award of contract
five.2.1) Date of conclusion of the contract
21 October 2025
five.2.2) Information about tenders
Number of tenders received: 3
The contract has been awarded to a group of economic operators: No
five.2.3) Name and address of the contractor
Guy's and St Thomas' NHS Foundation Trust
London
Country
United Kingdom
NUTS code
- UKI3 - Inner London – West
The contractor is an SME
No
five.2.4) Information on value of contract/lot (excluding VAT)
Total value of the contract/lot: £5,175,000,000
Section six. Complementary information
six.3) Additional information
This is a Provider Selection Regime (PSR) intention to award notice. This intention to award notice is subject to Regulation 10(7) of the Health Care Services (Provider Selection Regime) Regulations 2023. For the avoidance of doubt, the provisions of the Procurement Act Regulations 2023 do not apply to this award. The standstill period begins on the day after the publication of this notice. Representations by providers must be made to the relevant authority by midnight on Tuesday 4th November 2025. This contract has not yet formally been awarded; this notice serves as an intention to award under the PSR.
Written representations should be sent to england.genomics@nhs.net, ensuring the following details are referenced:
Project reference: C368833
Project title: NHS Genomic Medicine Service - Most Suitable Provider process
This decision has been made as per NHS England governance processes, by the Commercial Executive Group on 14th October 2025 and the National Commissioning Group on 21st October 2025. No conflicts of Interest were identified amongst decision-makers.
Each of the 5 key criteria were balanced with equal priority and considered on this basis and consideration was given to the basic selection criteria. Following provider assessments, it was agreed that the providers are the only providers capable of meeting the service specifications and requirements of the NHS GMS in full.
Additional CPV codes include:
85145000-7 (Services provided by medical laboratories),
85148000-8 (Medical analysis services)
85111810-1 (Blood analysis services)
85121200-5 (Medical specialist services)
85140000-2 (Miscellaneous health services)
six.4) Procedures for review
six.4.1) Review body
NHS Arden and Greater East Midlands Commissioning Support Unit
Cardinal Square, 10 Nottingham Road
Derby
DE1 3QT
Country
United Kingdom