Scope
Reference
C346388
Description
NHS National Framework for Medical Retinal Vascular Treatments - 1 December 2025
Offer reference number: CM/PHS/25/5728
Period of framework agreement: Dates detailed below, with an option or options to extend (at the discretion of the Authority) up to maximum of 24 months.
Potential periods of call-offs under the framework agreement:
CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments:
7NAT (National) 01/12/2025 to 31/05/2027 (18 months)
CM/PHS/25/5728/02 - Regional Framework for Medical Retinal Vascular Treatments aflibercept 2mg:
NOFE: (North of England) 01/12/2025 to 31/05/2027 (18 months)
SOFE: (South of England) 01/12/2025 to 31/05/2027 (18 months)
MAE: (Midlands and East) 01/12/2025 to 31/05/2027 (18 months)
LNW: (London) 01/12/2025 to 31/05/2027 (18 months)
Published By: Medicines Procurement and Supply Chain - NHS Medicines Value & Access, NHS England
Provision of Licensed Medical Retinal Vascular Anti Veg-F and Intravitreal Corticosteroid medicines used in medical retinal vascular services for the NHS in England. To include but not limited to aflibercept, bevacizumab, brolucizumab, intravitreal dexamethasone, intravitreal fluocinolone, faricimab and ranibizumab used in the treatment of;
• neovascular (wet) age-related macular degeneration (AMD)
• visual impairment due to macular oedema secondary to retinal vein occlusion (branch RVO or central RVO)
• proliferative diabetic retinopathy (PDR)
• visual impairment due to diabetic macular oedema (DME)
• visual impairment due to diabetic macular oedema (DME) who are pseudophakic or who are considered insufficiently responsive to, or unsuitable for non-corticosteroid therapy
• vision impairment associated with chronic diabetic macular oedema, (DME)
• visual impairment due to myopic choroidal neovascularisation (myopic CNV)
• retinopathy of prematurity (ROP) with zone I (stage 1+, 2+, 3 or 3+), zone II (stage 2+ or 3+) or AP-ROP (aggressive posterior ROP) disease
• inflammation of the posterior segment of the eye presenting as non-infectious uveitis
• prevention of relapse in recurrent non-infectious uveitis affecting the posterior segment of the eye
Commercial tool
Establishes a framework
Lot 1. CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments:
Description
CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments: 7NAT (National)
Framework
Maximum percentage fee charged to suppliers
0%
Framework operation description
Please refer to the ITO Documents for the Operation Description.
Award method when using the framework
Without competition
Contracting authorities that may use the framework
Please refer to Document No. 09 in the ITO Documents for the list of Purchasing Points
Contracting authority location restrictions
- UK - United Kingdom
Contract 2. Lot 1 - CM/PHS/25/5728/01
Lots
Lot 1. CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments:
Suppliers (10)
- Abbvie Ltd
- Alimera Sciences
- Bayer Plc
- Biogen
- Novartis Pharmaceuticals UK Ltd
- Orion Pharma (UK) Ltd
- Outlook Therapeutics, Inc.
- Roche Products Ltd
- Teva UK Limited
- Thornton and Ross Ltd
Contract value
- £688,834,174 excluding VAT
- £826,601,009 including VAT
Above the relevant threshold
Date signed
22 September 2025
Contract dates
- 1 December 2025 to 31 May 2027
- Possible extension to 31 May 2029
- 3 years, 6 months
Description of possible extension:
option or options to extend (at the discretion of the Authority) up to maximum of 24 months.
Main procurement category
Goods
CPV classifications
- 33600000 - Pharmaceutical products
Key performance indicators
| Name | Description | Reporting frequency |
|---|---|---|
| Buffer Stock requirement | 6 months Buffer Stock |
3 months |
Signed contract documents
Framework Agreement and Terms and Conditions - Lot 1.pdf
Framework Agreement and Terms and Conditions - Lot 1
Contract 3. Lot 2 - CM/PHS/25/5728/02
Lots
Lot 1. CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments:
Suppliers (5)
- Bayer Plc
- BIOSIMILAR COLLABORATIONS IRELAND LIMITED
- Celltrion Healthcare United Kingdom Limited
- MDBIOLOGICS LTD
- SANDOZ LIMITED
Contract value
- £782,917,972 excluding VAT
- £939,501,566 including VAT
Above the relevant threshold
Date signed
22 September 2025
Contract dates
- 1 December 2025 to 31 May 2027
- Possible extension to 31 May 2029
- 3 years, 6 months
Description of possible extension:
option or options to extend (at the discretion of the Authority) up to maximum of 24 months.
Main procurement category
Goods
CPV classifications
- 33600000 - Pharmaceutical products
Key performance indicators
| Name | Description | Reporting frequency |
|---|---|---|
| Buffer Stock | 6 months Buffer Stock |
3 months |
Signed contract documents
Framework Agreement and Terms and Conditions - Lot 2.pdf
Framework Agreement and Terms and Conditions - Lot 2
Other information
Conflicts assessment prepared/revised
Yes
Procedure
Procedure type
Open procedure
Suppliers
Abbvie Ltd
- Public Procurement Organisation Number: PHRQ-1133-WGCH
Abbvie House Vanwall Business Park
Maidenhead
SL6 4UB
United Kingdom
Email: val.stenning@abbvie.com
Region: UKJ11 - Berkshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
Alimera Sciences
- Public Procurement Organisation Number: PYCZ-7339-TCCT
Form 1 Bartley Wood Business Park
Hook
RG27 9XA
United Kingdom
Region: UKJ37 - North Hampshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
Bayer Plc
- Public Procurement Organisation Number: PWRY-2527-LDRY
400 South Oak Way
Reading
RG2 6AD
United Kingdom
Email: andrew.asbury@bayer.com
Region: UKJ11 - Berkshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 3. Lot 2 - CM/PHS/25/5728/02
Bayer Plc
- Companies House: 00935048
400 South Oak Way
Reading
RG26AD
United Kingdom
Email: andrew.asbury@bayer.com
Region: UKJ11 - Berkshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
Biogen
- Public Procurement Organisation Number: PTGT-3385-PBMQ
Building 5 Foundation Park
Maidenhead
SL63UD
United Kingdom
Email: bbumarketaccessuk@biogen.com
Region: UKJ11 - Berkshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
BIOSIMILAR COLLABORATIONS IRELAND LIMITED
- Public Procurement Organisation Number: PQQC-5869-LMVX
Biocon Biologics 16 Great Queen Street
London
WC2B 5AH
United Kingdom
Email: uk_tenders@biocon.com
Region: UKI31 - Camden and City of London
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 3. Lot 2 - CM/PHS/25/5728/02
Celltrion Healthcare United Kingdom Limited
- Public Procurement Organisation Number: PYQL-4248-PXXY
Celltrion Healthcare UK Limited, The Charter Building, Charter Place
Uxbridge
UB8 1JG
United Kingdom
Email: james.potter@celltrionhc.com
Region: UKI74 - Harrow and Hillingdon
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 3. Lot 2 - CM/PHS/25/5728/02
MDBIOLOGICS LTD
- Public Procurement Organisation Number: PMHC-1596-RTNX
71-75 Shelton Street
London
WC2H 9JQ
United Kingdom
Email: paul.clark@mdbiologics.co.uk
Region: UKI31 - Camden and City of London
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 3. Lot 2 - CM/PHS/25/5728/02
Novartis Pharmaceuticals UK Ltd
- Public Procurement Organisation Number: PJTX-5182-QVLR
2nd Floor, The Westworks Building White City Place
London
W12 7FQ
United Kingdom
Email: commercial.team@novartis.com
Region: UKI33 - Kensington & Chelsea and Hammersmith & Fulham
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
Orion Pharma (UK) Ltd
- Public Procurement Organisation Number: PJZQ-1429-ZBVY
The Scalpel, 18th Floor
London
EC3M 7AF
United Kingdom
Region: UKI31 - Camden and City of London
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
Outlook Therapeutics, Inc.
- Public Procurement Organisation Number: PGZH-1763-NPGX
3rd Floor One London Square, Cross Lanes, Guildford,
Surrey
GU1 1UN
United Kingdom
Region: UKJ25 - West Surrey
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
Roche Products Ltd
- Public Procurement Organisation Number: PXCG-4172-CHYM
6 Falcon Way
Welwyn Garden City
AL7 1TW
United Kingdom
Email: welwyn.rx_bdop@roche.com
Region: UKH23 - Hertfordshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
SANDOZ LIMITED
- Public Procurement Organisation Number: PNQL-1548-CYBZ
Maxis 1, Western Road
Bracknell
RG12 1RF
United Kingdom
Email: uk.hosp@sandoz.com
Region: UKJ11 - Berkshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 3. Lot 2 - CM/PHS/25/5728/02
Teva UK Limited
- Public Procurement Organisation Number: PWDD-6894-DXRM
Ridings Point
Castleford
WF10 5HX
United Kingdom
Email: chrissie.kellett@tevauk.com
Region: UKE45 - Wakefield
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
Thornton and Ross Ltd
- Public Procurement Organisation Number: PWYH-6892-QYNN
Linthwaite Labs Manchester Road
Huddersfield
HD7 5QH
United Kingdom
Region: UKE44 - Calderdale and Kirklees
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 1 - CM/PHS/25/5728/01
Contracting authority
NHS England
- Public Procurement Organisation Number: PDPT-3135-BWWY
Wellington House, 133-135 Waterloo Rd
London
SE1 8UG
United Kingdom
Region: UKI45 - Lambeth
Organisation type: Public authority - central government