Scope
Reference
GEL-RE-25161
Description
Genomics England is procuring long-read whole genome sequencing services. In partnership with the NHS and other stakeholders, we are co-designing and delivering a national research study, the Generation Study, involving up to 100,000 newborns to understand the role of whole genome sequencing to achieve more timely diagnosis of rare conditions and access to early intervention, enabling faster and better care for babies born with rare childhood onset diseases. The Generation Study aims to assess the benefits, challenges, and feasibility of integrating whole genome sequencing into newborn screening to enhance the early diagnosis and treatment of rare genetic conditions. If successful, the study could establish the foundation for the world's first national newborn screening program incorporating whole genome sequencing.
The study also aims to understand how, with consent, newborns' genomic and health data could be used for research to enable new diagnostic discoveries and treatments to be developed. As part of the consent to the study mothers are asked for permission to retain the baby's data and sample and link it to clinical data over the course of their life and the ability to recontact them with further research opportunities.
The study will provide an invaluable dataset to researchers across industry and academia, and we have the opportunity to conduct further studies in a subset of these families to maximise the future impact to patients, researchers and the NHS. Deepening our dataset, including by introducing new modalities, is a priority for industry.
To do this, we to plan to develop an enhanced longitudinal birth cohort (Babies in Focus) in a subset of participants in the next five years. This will begin with conducting long-read whole genome sequencing for at least 2,000 samples across two long-read technologies. This will help inform us of the plans for the larger funding that is being requested as part of the 2026-2030 spending review.
These services will be split into two lots:
Lot 1: 1,000 samples to be delivered to the supplier and sequenced between 5 January 2026 and 31 March 2026 using ONT technology. An earlier start date may be mutually agreed by the Supplier and the Authority if implementation is completed before 5 January 2026.
Lot 2: 1,000 samples to be delivered and sequenced between 1 April 2026 and 1 September 2026 using PacBio technology. An earlier start date may be mutually agreed by Supplier and the Authority, subject to the Supplier's willingness and capability, and Authority funding.
There is an optional extension (volume to be confirmed) of up to a total of 1,000 additional samples. These optional extension volumes may be awarded to one or split across both lots. These optional volumes must be delivered by 1 March 2027.
Lot 1. 2025-2026
Description
1,000 samples to be delivered to the Supplier and sequenced between 5 January 2026 and 31 March 2026. An earlier start date may be mutually agreed by the Supplier and the Authority if implementation is completed before 5 January 2026. Please note that the estimated value of Lot 1 is £1.4M.There is an optional extension (volume to be confirmed) of up to a total of 1,000 additional samples, valued at £1.4M. These optional extension volumes may be awarded to one or split across both lots. These optional volumes must be delivered by 1 March 2027.
Lot 2. 2026-2027
Description
1,000 samples to be delivered and sequenced between 1 April 2026 and 1 September 2026. An earlier start date may be mutually agreed by Supplier and Authority, subject to the Supplier's willingness and capability, and Authority funding. Please note that the estimated value of Lot 2 is £1.4M.There is an optional extension (volume to be confirmed) of up to a total of 1,000 additional samples, valued at £1.4M. These optional extension volumes may be awarded to one or split across both lots. These optional volumes must be delivered by 1 March 2027.
Contract 1. 2025-2026
Lots
Lot 1. 2025-2026
Supplier
Contract value
- £2,206,318.20 excluding VAT
- £2,647,581.84 including VAT
Above the relevant threshold
Award decision date
26 September 2025
Date assessment summaries were sent to tenderers
26 September 2025
Standstill period
- End: 7 October 2025
- 8 working days
Earliest date the contract will be signed
21 October 2025
Contract dates (estimated)
- 21 October 2025 to 31 March 2026
- Possible extension to 1 March 2027
- 1 year, 4 months, 12 days
Description of possible extension:
There is an optional extension (volume to be confirmed) of up to a total of 1,000 additional samples. These optional extension volumes may be awarded to one or split across both lots. The potential cost of this has been taken into account and forms part of the maximum contract value. These optional volumes must be delivered by 1 March 2027.
Main procurement category
Services
CPV classifications
- 73111000 - Research laboratory services
- 85145000 - Services provided by medical laboratories
- 85148000 - Medical analysis services
Contract locations
- UKC - North East (England)
- UKD - North West (England)
- UKE - Yorkshire and the Humber
- UKF - East Midlands (England)
- UKG - West Midlands (England)
- UKH - East of England
- UKI - London
- UKJ - South East (England)
- UKK - South West (England)
Contract 2. 2026-2027
Lots
Lot 2. 2026-2027
Supplier
Contract value
- £1,288,000 excluding VAT
- £1,545,600 including VAT
Above the relevant threshold
Award decision date
26 September 2025
Date assessment summaries were sent to tenderers
26 September 2025
Standstill period
- End: 7 October 2025
- 8 working days
Earliest date the contract will be signed
21 October 2025
Contract dates (estimated)
- 1 April 2026 to 1 September 2026
- Possible extension to 1 March 2027
- 11 months, 1 day
Description of possible extension:
There is an optional extension (volume to be confirmed) of up to a total of 1,000 additional samples. These optional extension volumes may be awarded to one or split across both lots. The potential cost of this has been taken into account and forms part of the maximum contract value. These optional volumes must be delivered by 1 March 2027.
Main procurement category
Services
CPV classifications
- 73111000 - Research laboratory services
- 85145000 - Services provided by medical laboratories
- 85148000 - Medical analysis services
Contract locations
- UKC - North East (England)
- UKD - North West (England)
- UKE - Yorkshire and the Humber
- UKF - East Midlands (England)
- UKG - West Midlands (England)
- UKH - East of England
- UKI - London
- UKJ - South East (England)
- UKK - South West (England)
Information about tenders
Lot 1. 2025-2026
- 7 tenders received
- 7 tenders assessed in the final stage:
- 3 submitted by small and medium-sized enterprises (SME)
- 0 submitted by voluntary, community and social enterprises (VCSE)
- 1 supplier awarded contracts
- 6 suppliers unsuccessful (details included for contracts over £5 million)
Lot 2. 2026-2027
- 7 tenders received
- 7 tenders assessed in the final stage:
- 3 submitted by small and medium-sized enterprises (SME)
- 0 submitted by voluntary, community and social enterprises (VCSE)
- 1 supplier awarded contracts
- 6 suppliers unsuccessful (details included for contracts over £5 million)
Procedure
Procedure type
Open procedure
Suppliers
CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED
- Companies House: 05749230
- Public Procurement Organisation Number: PNYY-3754-WGCG
The Old Schools
Cambridge
CB2 1TS
United Kingdom
Email: cs.admin@enterprise.cam.ac.uk
Website: https://www.enterprise.cam.ac.uk/
Region: UKH12 - Cambridgeshire CC
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. 2025-2026
EUROFINS GENOMICS UK LIMITED
- Companies House: 03297407
- Public Procurement Organisation Number: PBHC-9469-NGRH
I54 Busines Park
Wolverhampton
WV9 5GB
United Kingdom
Email: tenders@genomics.eurofinseu.com
Website: http://www.eurofinsgenomics.com
Region: UKG24 - Staffordshire CC
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. 2026-2027
Contracting authority
GENOMICS ENGLAND LIMITED
- Companies House: 08493132
- Public Procurement Organisation Number: PBTW-5897-QJGY
Level 21 One Canada Square
London
E14 5AB
United Kingdom
Region: UKI42 - Tower Hamlets
Organisation type: Public authority - central government