Scope
Reference
C346388
Description
NHS National Framework for Medical Retinal Vascular Treatments - 1 December 2025
Offer reference number: CM/PHS/25/5728
Period of framework agreement: Dates detailed below, with an option or options to extend (at the discretion of the Authority) up to maximum of 24 months.
Potential periods of call-offs under the framework agreement:
CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments:
7NAT (National) 01/12/2025 to 31/05/2027 (18 months)
CM/PHS/25/5728/02 - Regional Framework for Medical Retinal Vascular Treatments aflibercept 2mg:
NOFE: (North of England) 01/12/2025 to 31/05/2027 (18 months)
SOFE: (South of England) 01/12/2025 to 31/05/2027 (18 months)
MAE: (Midlands and East) 01/12/2025 to 31/05/2027 (18 months)
LNW: (London) 01/12/2025 to 31/05/2027 (18 months)
Published By: Medicines Procurement and Supply Chain - NHS Medicines Value & Access, NHS England
Provision of Licensed Medical Retinal Vascular Anti Veg-F and Intravitreal Corticosteroid medicines used in medical retinal vascular services for the NHS in England. To include but not limited to aflibercept, bevacizumab, brolucizumab, intravitreal dexamethasone, intravitreal fluocinolone, faricimab and ranibizumab used in the treatment of;
• neovascular (wet) age-related macular degeneration (AMD)
• visual impairment due to macular oedema secondary to retinal vein occlusion (branch RVO or central RVO)
• proliferative diabetic retinopathy (PDR)
• visual impairment due to diabetic macular oedema (DME)
• visual impairment due to diabetic macular oedema (DME) who are pseudophakic or who are considered insufficiently responsive to, or unsuitable for non-corticosteroid therapy
• vision impairment associated with chronic diabetic macular oedema, (DME)
• visual impairment due to myopic choroidal neovascularisation (myopic CNV)
• retinopathy of prematurity (ROP) with zone I (stage 1+, 2+, 3 or 3+), zone II (stage 2+ or 3+) or AP-ROP (aggressive posterior ROP) disease
• inflammation of the posterior segment of the eye presenting as non-infectious uveitis
• prevention of relapse in recurrent non-infectious uveitis affecting the posterior segment of the eye
Commercial tool
Establishes a framework
Lot 1. CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments:
Description
CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments: 7NAT (National)
Lot 2. CM/PHS/25/5728/02 - Regional Framework for Medical Retinal Vascular Treatments a
Description
CM/PHS/25/5728/02 - Regional Framework for Medical Retinal Vascular Treatments aflibercept 2mg
Contract 1. Lot 1 - CM/PHS/25/5728/01
Lots
Lot 1. CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments:
Suppliers (10)
- ABBVIE LTD
- ALIMERA SCIENCES LIMITED
- BAYER PUBLIC LIMITED COMPANY
- BIOGEN IDEC LIMITED
- NOVARTIS PHARMACEUTICALS UK LIMITED
- ORION PHARMA (UK) LIMITED
- Outlook Therapeutics, Inc.
- ROCHE PRODUCTS LIMITED
- TEVA UK LIMITED
- THORNTON & ROSS LIMITED
Contract value
- £688,834,174 excluding VAT
- £826,601,009 including VAT
Framework lot values may be shared with other lots
Above the relevant threshold
Award decision date
31 July 2025
Date assessment summaries were sent to tenderers
31 July 2025
Standstill period
- End: 13 August 2025
- 8 working days
Earliest date the contract will be signed
18 August 2025
Contract dates (estimated)
- 1 December 2025 to 31 May 2027
- Possible extension to 31 May 2029
- 3 years, 6 months
Description of possible extension:
option or options to extend (at the discretion of the Authority) up to maximum of 24 months.
Main procurement category
Goods
CPV classifications
- 33600000 - Pharmaceutical products
Contract locations
- UKC - North East (England)
- UKD - North West (England)
- UKE - Yorkshire and the Humber
- UKF - East Midlands (England)
- UKG - West Midlands (England)
- UKH - East of England
- UKI - London
- UKJ - South East (England)
- UKK - South West (England)
Contract 2. Lot 2 - CM/PHS/25/5728/02
Lots
Lot 2. CM/PHS/25/5728/02 - Regional Framework for Medical Retinal Vascular Treatments a
Suppliers (5)
- BAYER PUBLIC LIMITED COMPANY
- Biosimilar Collaborations Ireland Limited
- CELLTRION HEALTHCARE UNITED KINGDOM LIMITED
- MDBIOLOGICS LTD
- SANDOZ LIMITED
Contract value
- £782,917,972 excluding VAT
- £939,501,566 including VAT
Framework lot values may be shared with other lots
Above the relevant threshold
Award decision date
31 July 2025
Date assessment summaries were sent to tenderers
31 July 2025
Standstill period
- End: 13 August 2025
- 8 working days
Earliest date the contract will be signed
18 August 2025
Contract dates (estimated)
- 1 December 2025 to 31 May 2027
- Possible extension to 31 May 2029
- 3 years, 6 months
Description of possible extension:
option or options to extend (at the discretion of the Authority) up to maximum of 24 months.
Main procurement category
Goods
CPV classifications
- 33600000 - Pharmaceutical products
Contract locations
- UKC - North East (England)
- UKD - North West (England)
- UKE - Yorkshire and the Humber
- UKF - East Midlands (England)
- UKG - West Midlands (England)
- UKH - East of England
- UKI - London
- UKJ - South East (England)
- UKK - South West (England)
Information about tenders
Lot 1. CM/PHS/25/5728/01 - National Framework for Medical Retinal Vascular Treatments:
- 11 tenders received
- 11 tenders assessed in the final stage:
- 4 submitted by small and medium-sized enterprises (SME)
- 0 submitted by voluntary, community and social enterprises (VCSE)
- 10 suppliers awarded contracts
- 1 supplier unsuccessful (details included for contracts over £5 million)
Unsuccessful suppliers
Lot 2. CM/PHS/25/5728/02 - Regional Framework for Medical Retinal Vascular Treatments a
- 7 tenders received
- 7 tenders assessed in the final stage:
- 1 submitted by small and medium-sized enterprises (SME)
- 0 submitted by voluntary, community and social enterprises (VCSE)
- 5 suppliers awarded contracts
- 2 suppliers unsuccessful (details included for contracts over £5 million)
Unsuccessful suppliers
Procedure
Procedure type
Open procedure
Suppliers
ABBVIE LTD
- Companies House: 08004972
- Public Procurement Organisation Number: PHRQ-1133-WGCH
Abbvie House Vanwall Business Park
Maidenhead
SL6 4UB
United Kingdom
Email: carol.woodland@abbvie.com
Website: http://www.abbvie.co.uk/
Region: UKJ11 - Berkshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
ALIMERA SCIENCES LIMITED
- Companies House: 08018355
- Public Procurement Organisation Number: PYCZ-7339-TCCT
Form 1 Bartley Wood Business Park
Hook
RG27 9XA
United Kingdom
Region: UKJ37 - North Hampshire
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
AMGEN LIMITED
- Companies House: 02354269
- Public Procurement Organisation Number: PDJG-8184-TCQQ
216 Cambridge Science Park
Cambridge
CB4 0WA
United Kingdom
Website: http://www.amgen.co.uk
Region: UKH12 - Cambridgeshire CC
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
BAYER PUBLIC LIMITED COMPANY
- Companies House: 00935048
- Public Procurement Organisation Number: PWRY-2527-LDRY
400 South Oak Way
Reading
RG2 6AD
United Kingdom
Email: andrew.asbury@bayer.com
Website: http://www.bayer.co.uk
Region: UKJ11 - Berkshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
Contract 2. Lot 2 - CM/PHS/25/5728/02
BIOGEN IDEC LIMITED
- Companies House: 01497267
- Public Procurement Organisation Number: PTGT-3385-PBMQ
Building 5 Foundation Park
Maidenhead
SL6 3UD
United Kingdom
Email: bbumarketaccessuk@biogen.com
Website: https://www.biogen-uk-ie.com
Region: UKJ11 - Berkshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
Biosimilar Collaborations Ireland Limited
- Public Procurement Organisation Number: PQQC-5869-LMVX
Unit 35/36 Grange Parade, Baldoyle Industrial Estate, Dublin 13
DUBLIN
D13 R20R
Ireland
Email: uk_tenders@biocon.com
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 2 - CM/PHS/25/5728/02
CELLTRION HEALTHCARE UNITED KINGDOM LIMITED
- Companies House: 11685363
- Public Procurement Organisation Number: PYQL-4248-PXXY
The Charter Building
Uxbridge
UB8 1JG
United Kingdom
Email: info@celltrionhc.com
Region: UKI74 - Harrow and Hillingdon
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 2 - CM/PHS/25/5728/02
MDBIOLOGICS LTD
- Companies House: 15579040
- Public Procurement Organisation Number: PMHC-1596-RTNX
71-75 Shelton Street
London
WC2H 9JQ
United Kingdom
Email: paul.clark@mdbiologics.co.uk
Website: http://www.mdbiologics.co.uk
Region: UKI31 - Camden and City of London
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 2 - CM/PHS/25/5728/02
MERCURY PHARMACEUTICALS LIMITED
- Companies House: 02619880
- Public Procurement Organisation Number: PHGH-5788-VVDL
Dashwood House
London
EC2M 1QS
United Kingdom
Website: http://www.advanzpharma.com
Region: UKI31 - Camden and City of London
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
NOVARTIS PHARMACEUTICALS UK LIMITED
- Companies House: 00119006
- Public Procurement Organisation Number: PJTX-5182-QVLR
2nd Floor, The Westworks Building White City Place
London
W12 7FQ
United Kingdom
Email: commercial.pricing@novartis.com
Website: https://www.novartis.com/uk-en/
Region: UKI33 - Kensington & Chelsea and Hammersmith & Fulham
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
ORIFARM UK LTD
- Companies House: 10015046
- Public Procurement Organisation Number: PQPW-1715-PJLT
Ground Floor, Suite A2 Breakspear Way
Hemel Hempstead
HP2 4TZ
United Kingdom
Website: http://www.orifarm.com
Region: UKH23 - Hertfordshire
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
ORION PHARMA (UK) LIMITED
- Companies House: 02281057
- Public Procurement Organisation Number: PJZQ-1429-ZBVY
The Scalpel, 18th Floor
London
EC3M 7AF
United Kingdom
Email: mark.soderberg@orionpharma.com
Website: http://www.orionpharma.co.uk
Region: UKI31 - Camden and City of London
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
Outlook Therapeutics, Inc.
- Companies House: 08179857
- Public Procurement Organisation Number: PGZH-1763-NPGX
111 S. Wood Ave Unit
#100 Iselin
NJ 08830
United States
Small or medium-sized enterprise (SME): Yes
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
ROCHE PRODUCTS LIMITED
- Companies House: 00100674
- Public Procurement Organisation Number: PXCG-4172-CHYM
6 Falcon Way
Welwyn Garden City
AL7 1TW
United Kingdom
Email: welwyn.rx_bdop@roche.com
Website: https://www.roche.co.uk/
Region: UKH23 - Hertfordshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
SANDOZ LIMITED
- Companies House: 01547204
- Public Procurement Organisation Number: PNQL-1548-CYBZ
Maxis 1, Western Road
Bracknell
RG12 1RF
United Kingdom
Email: uk.tenders@sandoz.com
Website: http://www.sandoz.com
Region: UKJ11 - Berkshire
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 2. Lot 2 - CM/PHS/25/5728/02
TEVA UK LIMITED
- Companies House: 00302461
- Public Procurement Organisation Number: PWDD-6894-DXRM
Ridings Point
Castleford
WF10 5HX
United Kingdom
Email: chrissie.kellett@tevauk.com
Website: http://www.tevauk.com
Region: UKE45 - Wakefield
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
THORNTON & ROSS LIMITED
- Companies House: 00185947
- Public Procurement Organisation Number: PWYH-6892-QYNN
Linthwaite Labs Manchester Road
Huddersfield
HD7 5QH
United Kingdom
Email: hospitalcontracts@throntonross.com
Website: https://www.thorntonross.com/
Region: UKE44 - Calderdale and Kirklees
Small or medium-sized enterprise (SME): No
Voluntary, community or social enterprise (VCSE): No
Supported employment provider: No
Public service mutual: No
Contract 1. Lot 1 - CM/PHS/25/5728/01
Contracting authority
NHS ENGLAND
- NHS Organisation Data Service: X24
- Public Procurement Organisation Number: PDPT-3135-BWWY
NHS England, 7&8 Wellington Place
Leeds
LS1 4AP
United Kingdom
Contact name: Balram Kullootee
Email: b.kullootee@nhs.net
Region: UKE42 - Leeds
Organisation type: Public authority - central government