Contract

Term Framework for the Provision of Chemistry Synthesis and other Chemistry Services Outsourcing Framework

  • University of Dundee

F03: Contract award notice

Notice identifier: 2024/S 000-038232

Procurement identifier (OCID): ocds-h6vhtk-044ba4

Published 26 November 2024, 5:00pm



Section one: Contracting authority

one.1) Name and addresses

University of Dundee

Procurement, 3rd Floor, Tower Building, Nethergate

Dundee

DD1 4HN

Contact

Mary Kirkpatrick

Email

m.y.kirkpatrick@dundee.ac.uk

Telephone

+44 1382386604

Country

United Kingdom

NUTS code

UKM71 - Angus and Dundee City

Internet address(es)

Main address

http://www.dundee.ac.uk

Buyer's address

https://www.publiccontractsscotland.gov.uk/search/Search_AuthProfile.aspx?ID=AA00105

one.2) Information about joint procurement

The contract is awarded by a central purchasing body

one.4) Type of the contracting authority

Body governed by public law

one.5) Main activity

Education


Section two: Object

two.1) Scope of the procurement

two.1.1) Title

Term Framework for the Provision of Chemistry Synthesis and other Chemistry Services Outsourcing Framework

Reference number

UoD-LAB031-TC-2023

two.1.2) Main CPV code

  • 73110000 - Research services

two.1.3) Type of contract

Services

two.1.4) Short description

Second-Generation Framework for the provision of Chemistry Synthesis and other Chemistry Services Outsourcing with initial term of two (2) years with the option to extend for up to 2 x 12 months, if required, at the sole discretion of the University and subject to ongoing satisfactory performance by the appointed Service Providers.

The Services will include:

1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;

2.Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;

3. Scale up of chemistry, up to 200g;

4.Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.

5.Synthesis of intermediates at 5-100g;

For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;

6. Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.

two.1.6) Information about lots

This contract is divided into lots: No

two.1.7) Total value of the procurement (excluding VAT)

Value excluding VAT: £1,000,000

two.2) Description

two.2.2) Additional CPV code(s)

  • 73110000 - Research services

two.2.3) Place of performance

NUTS codes
  • UKM71 - Angus and Dundee City
Main site or place of performance

Biological Chemistry & Drug Discovery (BCDD), University of Dundee

two.2.4) Description of the procurement

This Second-Generation Framework is required to provide a quick route to market for the provision of Chemistry Synthesis and other Chemistry Services. The initial contract term will be two (2) years, with the option to extend for 2 x 12 months, if required, at the sole discretion of BCDD and subject to ongoing satisfactory performance by the appointed Service Providers

The Chemistry Synthesis and Other Chemistry Services required will include:

1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;

2. Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;

-Scale up of chemistry, up to 200g;

-Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.

-Synthesis of intermediates at 5-100g;

For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;

-Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.

The subsequent route to market will be via Mini Comp under the Framework.

two.2.5) Award criteria

Quality criterion - Name: 1. Account /Project Management & Communication / Weighting: 4

Quality criterion - Name: 2.Range of Chemistry Synthesis and other Chemistry Services available. / Weighting: 10

Quality criterion - Name: 3. Service Levels / Weighting: 10

Quality criterion - Name: 4. Audit Control & Record Keeping / Weighting: 10

Quality criterion - Name: 5. Sample CVs / Weighting: 2

Quality criterion - Name: 6. Added Value / Weighting: 4

Price - Weighting: 60

two.2.11) Information about options

Options: No

two.2.13) Information about European Union Funds

The procurement is related to a project and/or programme financed by European Union funds: No


Section four. Procedure

four.1) Description

four.1.1) Type of procedure

Open procedure

four.1.3) Information about a framework agreement or a dynamic purchasing system

The procurement involves the establishment of a framework agreement

four.1.8) Information about the Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: Yes

four.2) Administrative information

four.2.1) Previous publication concerning this procedure

Notice number: 2024/S 000-009350


Section five. Award of contract

Contract No

UoD-LAB031-TC-2023

A contract/lot is awarded: Yes

five.2) Award of contract

five.2.1) Date of conclusion of the contract

22 July 2024

five.2.2) Information about tenders

Number of tenders received: 11

Number of tenders received from SMEs: 4

Number of tenders received from tenderers from other EU Member States: 2

Number of tenders received from tenderers from non-EU Member States: 9

Number of tenders received by electronic means: 11

The contract has been awarded to a group of economic operators: Yes

five.2.3) Name and address of the contractor

TCG Lifesciences

Block BN, Plot 7, Saltlake Electronics Complex, Sector V

Kolkata, West Bengal, India

700091

Telephone

+001 9194142706

Country

Kosovo

NUTS code
  • 1A - Kosovo
The contractor is an SME

No

five.2.3) Name and address of the contractor

3xper Innoventure Limited

Ticel Bio Park (Phase-2), 7th floor, Taramani

Chennai, Tamil Nadu

600113

Telephone

+91 4440037721

Country

India

NUTS code
  • IN - India
The contractor is an SME

No

five.2.3) Name and address of the contractor

SYNGENE INTERNATIONAL LIMITED

BIOCON SPECIAL ECONOMIC ZONE, BIOCON PARK, PLOT NO. 2 & 3, IV PHASE, BOMMASANDRA INDUSTRIAL AREA,BOMMASANDRA-JIGANI LINK ROAD

BANGALORE

560099

Email

nan.zhao@syngeneintl.com

Telephone

+44 7414206297

Country

India

NUTS code
  • IN - India
The contractor is an SME

No

five.2.3) Name and address of the contractor

BioAscent Discovery Ltd

Bo'ness rd

Newhouse

ML1 5UH

Email

asmith@bioascent.com

Telephone

+44 1698534002

Country

United Kingdom

NUTS code
  • UKM84 - North Lanarkshire
The contractor is an SME

No

five.2.3) Name and address of the contractor

Jubilant Biosys Limited

#96, Industrial Suburb, 2nd Stage, Yeshwanthpur

Bangalore

560022

Telephone

+91 9886641533

Country

India

NUTS code
  • IN - India
The contractor is an SME

No

five.2.3) Name and address of the contractor

Cambridge Bioscience

Munro House

Cambridge

CB 23 8SQ

Email

hiten.patel@bioscience.co.uk

Telephone

+44 1223316855

Country

United Kingdom

NUTS code
  • UK - United Kingdom
The contractor is an SME

No

five.2.3) Name and address of the contractor

Chemveda Life Sciences India Pvt. Ltd.

Plot- B 11/1, IDA Uppal

Hyderabad, Telangana

500039

Country

India

NUTS code
  • IN - India
The contractor is an SME

No

five.2.3) Name and address of the contractor

Sai Life Sciences

Alderley Park

Macclesfield

SK104TG

Email

victoria.s@sailife.com

Telephone

+44 7789995203

Country

United Kingdom

NUTS code
  • UK - United Kingdom
The contractor is an SME

No

five.2.3) Name and address of the contractor

"ENAMINE" SIA

Vestienas iela 2 B

Riga

LV-1035

Telephone

+38 0444958814

Country

Latvia

NUTS code
  • LV006 - Rīga
The contractor is an SME

No

five.2.3) Name and address of the contractor

ChemPartner Europe ApS

Ole Maaloes Vej 3,

Copenhagen

2200

Telephone

+44 7768117764

Country

Denmark

NUTS code
  • DK - Denmark
The contractor is an SME

No

five.2.3) Name and address of the contractor

WuXi Apptec

5 New Street Square

London

EC4A 3TW

Telephone

+44 1279777142

Country

United Kingdom

NUTS code
  • UKI - London
The contractor is an SME

No

five.2.4) Information on value of contract/lot (excluding VAT)

Initial estimated total value of the contract/lot: £400,000

Total value of the contract/lot: £400,000


Section six. Complementary information

six.3) Additional information

(SC Ref:784022)

six.4) Procedures for review

six.4.1) Review body

Dundee Sheriff Court

West Bell Street

Dundee

DD1 1HN

Country

United Kingdom

six.4.2) Body responsible for mediation procedures

Dundee Sheriff Court

West Bell Street

Dundee

DD1 4HN

Country

United Kingdom