Section one: Contracting authority/entity
one.1) Name and addresses
Ministry of Defence
Salisbury Wiltshire
Country
United Kingdom
Region code
UK - United Kingdom
Internet address(es)
Main address
https://www.gov.uk/government/organisations/defence-science-and-technology-laboratory
Section two: Object
two.1) Scope of the procurement
two.1.1) Title
CORRIGENDUM - The Procurement of Active Pharmaceutical Ingredient Physostigmine Free Base
Reference number
Dstl/ADP/001-F01-PIN
two.1.2) Main CPV code
- 33661700 - Other nervous system medicinal products
two.1.3) Type of contract
Supplies
two.1.4) Short description
The purpose of this Prior Information Notice (PIN) is to:
• Share information on Dstl's current thinking regarding a requirement to supply a quantity of Physostigmine Free Base over the next 5-7 years, with the potential for a long term supply;
• Obtain views & feedback on this from the market, including responses to the questions detailed in this document;
• Provide the ability for the market to highlight areas of opportunity/innovation that Dstl are not currently aware of;
• Use the feedback & information to inform & support the development of the future Business Case(s) & Procurement Strategy.
This PIN questionnaire is not a request for a full proposal or bid nor should it be taken to be a call for competition, it is purely to obtain information from early engagement with the market.
In supporting a potential wider MOD requirement, Dstl is currently exploring the availability & capacity within the market to supply a quantity of the Active Pharmaceutical Ingredient (API), Physostigmine Free Base (also known as eserine; chemical name 1,2,3,3aβ,8,8aβ-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b] indol-5-yl-methylcarbamate; chemical formula C15H21N3O2; molecular weight 275,36 g/mol).
Under consideration is the development, process validation, manufacture & supply of this API with an outline indicative quantity of approx.15kg to 20kg per annum.
The PIN questionnaire is seeking to identify where possible that the ultimate requirement is market facing/realistic/deliverable & the potential cost of the approach.
Any information shared in response to the questionnaire, will be provided on the basis that it gives Dstl/UK MOD with free & unrestricted use of it in consideration of our requirement. It will not be shared outside of Dstl/UK MOD.
Dstl is also interested in responses that propose different approaches or areas of efficiency that subject matter experts consider could be deemed in scope. Dstl gives no guarantee whatsoever that such proposals will be taken forward.
Section six. Complementary information
six.6) Original notice reference
Notice number: 2022/S 000-012474
Section seven. Changes
seven.1) Information to be changed or added
seven.1.2) Text to be corrected in the original notice
Section number
VI.3
Place of text to be modified
Additional Information
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Text
To receive a copy of the PIN Questionnaire, please send an email with your point of contact information to: ADPProcurement@dstl.gov.uk
Section number
II.2.4
Place of text to be modified
Description of the Procurement
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Text
To receive a copy of the PIN Questionnaire, please send an email with your point of contact information to: ADPProcurement@dstl.gov.uk
Section number
II.2.2
Read
Additional CPV code(s)
- 33690000 - Various medicinal products
Section number
II.2.2
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Additional CPV code(s)
- 73300000 - Design and execution of research and development
Section number
VI.3
Instead of
Date
30 June 2022
Local time
11:59pm
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Date
30 November 2022
Local time
11:59pm
seven.2) Other additional information
Modification to the original information in the notice to provide interested economic operators with a process for obtaining the questionnaire relating to this PIN.