Section one: Contracting authority
one.1) Name and addresses
UNIVERSITY OF SHEFFIELD
THE UNIVERSITY OF SHEFFIELD,WESTERN BANK
SHEFFIELD
S102TN
Contact
James Noble
Country
United Kingdom
Region code
UKE32 - Sheffield
Companies House
RC000667
Internet address(es)
Main address
https://intendhost.co.uk/sheffield
one.3) Communication
The procurement documents are available for unrestricted and full direct access, free of charge, at
https://intendhost.co.uk/sheffield
Additional information can be obtained from the above-mentioned address
Tenders or requests to participate must be submitted electronically via
https://intendhost.co.uk/sheffield
one.4) Type of the contracting authority
Body governed by public law
one.5) Main activity
Education
Section two: Object
two.1) Scope of the procurement
two.1.1) Title
3900/JN/23 - Design and construction of an automated and compact mRNA GMP manufacturing system
Reference number
3900/JN/23
two.1.2) Main CPV code
- 73300000 - Design and execution of research and development
two.1.3) Type of contract
Services
two.1.4) Short description
Zoltan Kis from the University of Sheffield's department of Chemical and Biological Engineering with funding from Innovate UK is seeking a supplier to collaborate on the creation of an automated and compact GMP manufacturing system. The provider will be responsible for the design and prototyping of a custom system in-order to support the group's drive towards GMP, automated RNA production.
two.1.5) Estimated total value
Value excluding VAT: £760,000
two.1.6) Information about lots
This contract is divided into lots: No
two.2) Description
two.2.3) Place of performance
NUTS codes
- UKE32 - Sheffield
two.2.4) Description of the procurement
Zoltan Kis from the University of Sheffield's department of Chemical and Biological Engineering with funding from Innovate UK is seeking a supplier to collaborate on the creation of an automated and compact GMP manufacturing system. The provider will be responsible for the design and prototyping of a custom system in-order to support the group's drive towards GMP, automated RNA production.
The high-level work required is:
• The provider will work with The Kis Group to generate an engineering specification that meets their bioprocess. To achieve this the provider must have a working understanding of standard bioprocess techniques and have hands-on laboratory experience.
• The provider will generate high-level concepts to be discussed and reviewed by The Kis Group.
• The provider will then work with The Kis Group to allocate specific sections of work packages between the provider and The Kis Group.
• The provider will start by completing work packages that automate each of the individual RNA production steps (IVT, purification, LNP formation). For each of these work packages the provider will design concepts, review them with The Kis Group, generate manufacture files and source parts.
• The provider will assist The Kis Group in testing the sub-system prototypes in the biology lab. The provider must therefore have a team member with experience in biology labs.
• After subsystems are validated the provider will be responsible for designing a complete integrated system. Following concept design the provider will generate manufacturing documents and source components. The provider will work with The Kis Group to validate the integrated system against key bioprocess outputs.
two.2.5) Award criteria
Price is not the only award criterion and all criteria are stated only in the procurement documents
two.2.7) Duration of the contract, framework agreement or dynamic purchasing system
Duration in months
24
This contract is subject to renewal
No
two.2.10) Information about variants
Variants will be accepted: No
two.2.11) Information about options
Options: No
Section three. Legal, economic, financial and technical information
three.1) Conditions for participation
three.1.3) Technical and professional ability
Selection criteria as stated in the procurement documents
Section four. Procedure
four.1) Description
four.1.1) Type of procedure
Open procedure
four.1.8) Information about the Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement: Yes
four.2) Administrative information
four.2.2) Time limit for receipt of tenders or requests to participate
Date
17 October 2023
Local time
12:00pm
four.2.4) Languages in which tenders or requests to participate may be submitted
English
four.2.6) Minimum time frame during which the tenderer must maintain the tender
Duration in months: 3 (from the date stated for receipt of tender)
four.2.7) Conditions for opening of tenders
Date
17 October 2023
Local time
12:01pm
Section six. Complementary information
six.1) Information about recurrence
This is a recurrent procurement: No
six.2) Information about electronic workflows
Electronic ordering will be used
Electronic invoicing will be accepted
Electronic payment will be used
six.4) Procedures for review
six.4.1) Review body
University of Sheffield
Sheffield
S10 2TN
Country
United Kingdom