Planning

Molecular Screening Services

  • NHS Blood and Transplant

F01: Prior information notice (prior information only)

Notice identifier: 2023/S 000-007841

Procurement identifier (OCID): ocds-h6vhtk-03b3e2

Published 17 March 2023, 1:31pm



Section one: Contracting authority

one.1) Name and addresses

NHS Blood and Transplant

500 North Bristol Park

Bristol

BS34 7QH

Contact

Tennille Madigan

Email

tennille.madigan@nhsbt.nhs.uk

Telephone

+44 7795483583

Country

United Kingdom

Region code

UKK11 - Bristol, City of

Internet address(es)

Main address

https://www.nhsbt.nhs.uk/

Buyer's address

https://www.nhsbt.nhs.uk/

one.3) Communication

Additional information can be obtained from the above-mentioned address

Electronic communication requires the use of tools and devices that are not generally available. Unrestricted and full direct access to these tools and devices is possible, free of charge, at

https://health-family.force.com/s/Welcome

one.4) Type of the contracting authority

Body governed by public law

one.5) Main activity

Health


Section two: Object

two.1) Scope of the procurement

two.1.1) Title

Molecular Screening Services

two.1.2) Main CPV code

  • 33124130 - Diagnostic supplies

two.1.3) Type of contract

Supplies

two.1.4) Short description

This Prior Information Notice (PIN) is a call for competition and is separate to any tender opportunity. Its purpose is to inform the market of an up-and-coming tender opportunity. NHSBT are looking for a fully integrated high throughput testing solution for an automated Nucleic Acid Amplification Testing (NAT) system which can detect HBV DNA, HIV-1 RNA, HIV-2 RNA, HCV RNA, HEV RNA in EDTA plasma from blood and non-blood (e.g. stem cell, tissue) donors including from deceased (non-heart beating) donors. The solution must have the relevant CE/UKCA marking to support this ability.
Organisations who express an interest must declare this by 17th April 2023 including a statement confirming their current participation in a Kit Evaluation Group (KEG) evaluation, or their intention to join the KEG process, or confirmation that their testing solution has previously been KEG approved. Any organisations wishing to participate in the KEG evaluation process must also submit their relevant assay Instructions For Use (IFU) by 17th April 2023 to tennille.madigan@nhsbt.nhs.uk

Organisations who express an interest to participate will be invite to future engagement sessions in March/April 2023.

two.1.5) Estimated total value

Value excluding VAT: £3,800,000

two.1.6) Information about lots

This contract is divided into lots: No

two.2) Description

two.2.2) Additional CPV code(s)

  • 71900000 - Laboratory services
  • 48921000 - Automation system
  • 33696500 - Laboratory reagents
  • 33141625 - Diagnostic kits
  • 33124110 - Diagnostic systems
  • 33140000 - Medical consumables
  • 33124000 - Diagnostics and radiodiagnostic devices and supplies
  • 33696200 - Blood-testing reagents
  • 33127000 - Immuno-analysis devices
  • 33000000 - Medical equipments, pharmaceuticals and personal care products

two.2.3) Place of performance

NUTS codes
  • UK - United Kingdom
Main site or place of performance

Colindale

two.2.4) Description of the procurement

NHSBT requires a direct contractual relationship with either the manufacturer or any other economic operator for a complete end-to-end integrated solution, which must include all the necessary equipment, installation, maintenance, consumables, reagents, software, including an inter-operability provision with NHSBT’s existing IT infrastructure, and an overall on-going support mechanism that may be required to carry out the necessary testing as stated below.
All in vitro diagnostic medical devices, for example, instruments, consumables, and reagents must be CE/UKCA marked for specifically cadaveric donors.
Great Britain (GB) will continue to recognise CE marking under the IVDD or IVDR until 30 June 2024 and from 1 July 2024 devices placed on the GB market must be UKCA marked under the UK MDR 2002 as amended. The end-to-end solution must be capable of producing test results in a format that can be utilised by NHSBT’s host IT system. NHSBT are looking for a fully integrated, high throughput, automated Nucleic Acid Amplification Testing (NAT) screening system which can detect HBV DNA, HIV-1 RNA, HIV-2 RNA, HCV RNA, HEV RNA in EDTA plasma samples from blood and non-blood (e.g. stem cell, tissue) donors including samples from deceased (non-heart beating) donors, as individual donations i.e.: not pooled
Molecular Screening will be performed by NHSBTs Microbiology Services Laboratory in Colindale (London) with the following approximate number of samples (based on historical actual tests) per marker per year for both donation screening and confirmatory testing:
• HBV DNA: 7,381 screening tests as part of a multiplex & 1,082 individual tests for confirmatory testing
• HIV-1/HIV-2 RNA: 7,381 screening tests as part of a multiplex & 652 individual tests for confirmatory testing
• HCV RNA: 7,381 screening tests as part of a multiplex & 640 individual tests for confirmatory testing
• HEV RNA: 7,126 individual tests for either screening or confirmatory testing
• Pooling is not required, all samples will be tested as an individual donation.


It is important that interested parties respond to this PIN, as prior KEG approval will be a mandatory requirement for any associated future tender opportunity, in-line with the requirements of the Guidelines for the Blood Transfusion Services in the United Kingdom (Red Book - https://www.transfusionguidelines.org/red-book). NHSBT will seek to understand the status of assays which would be offered with regards to KEG. Any organisations wishing to participate in the KEG evaluation process must also submit their relating assay IFUs by 17th April 2023 to tennille.madigan@nhsbt.nhs.uk
Further details on KEG and the process will be provided during Supplier Engagement. The format of Supplier Engagement will be communicated to those organisations that respond to this PIN; however, this is likely to be virtual meetings conducted via Microsoft Teams during March/April 2023. Expressions of interest should be e-mailed to tennille.madigan@nhsbt.nhs.uk by 17th April 2023.

two.3) Estimated date of publication of contract notice

4 May 2023


Section four. Procedure

four.1) Description

four.1.8) Information about the Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: No