- Scope of the procurement
- Lot 1. Thrombotic Thrombocytopenic Purpura (TTP) – London and the South East (Kent, Surrey, East & West Sussex)
- Lot 2. Thrombotic Thrombocytopenic Purpura (TTP) - South East (Thames Valley, Hampshire and the Isle of Wight)
- Lot 3. Thrombotic Thrombocytopenic Purpura (TTP) - South West
- Lot 4. Thrombotic Thrombocytopenic Purpura (TTP) - West Midlands
- Lot 5. Thrombotic Thrombocytopenic Purpura (TTP) - East Midlands
- Lot 6. Thrombotic Thrombocytopenic Purpura (TTP) - East of England
- Lot 7. Thrombotic Thrombocytopenic Purpura (TTP) - North East
- Lot 8. Thrombotic Thrombocytopenic Purpura (TTP) - Yorkshire and the Humber
Section one: Contracting authority
one.1) Name and addresses
NHS England - Specialised Commissioning
80 London Road
London
SE1 6LH
Country
United Kingdom
NUTS code
UK - United Kingdom
National registration number
N/A
Internet address(es)
Main address
https://www.england.nhs.uk/commissioning/spec-services/
Buyer's address
https://www.ardengemcsu.nhs.uk/
one.3) Communication
The procurement documents are available for unrestricted and full direct access, free of charge, at
https://uk.eu-supply.com/ctm/supplier/publictenders?B=UK
Additional information can be obtained from the above-mentioned address
one.4) Type of the contracting authority
Body governed by public law
one.5) Main activity
Health
Section two: Object
two.1) Scope of the procurement
two.1.1) Title
NHS England Specialised Commissioning - Thrombotic Thrombocytopenic Purpura (TTP) all ages (up to 8 Lots)
Reference number
NHSSC-TPP-2021-NHS England
two.1.2) Main CPV code
- 85100000 - Health services
two.1.3) Type of contract
Services
two.1.4) Short description
Thrombotic Thrombocytopenic Purpura (TTP) is a serious blood disorder that results in blood clots forming in small blood vessels throughout the body. It affects the kidneys, heart and brain. If a patient is treated outside a specialist centre, mortality is 50%; in a specialist centre, it is 20%. There is also an appreciable acute morbidity, particularly in neurological disorders.
The condition can be difficult to diagnose because initial presentation can be non-specific and this is a very rare disease. Rapid treatment is essential for optimal outcomes and includes plasma exchange and a range of drugs. This disease primarily affects Adults. Children are treated in paediatric haematology centres and are outside the scope of this process.
Please see Section II.3 for complementary information.
two.1.6) Information about lots
This contract is divided into lots: Yes
two.2) Description
two.2.1) Title
Thrombotic Thrombocytopenic Purpura (TTP) – London and the South East (Kent, Surrey, East & West Sussex)
Lot No
1
two.2.2) Additional CPV code(s)
- 85000000 - Health and social work services
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKJ4 - Kent
- UKJ2 - Surrey, East and West Sussex
- UKI - London
Main site or place of performance
London and the South East (Kent, Surrey, East & West Sussex)
two.2.4) Description of the procurement
Thrombotic Thrombocytopenic Purpura (TTP) is a very rare, complex condition which can present as an acute life-threatening disorder that requires prompt diagnosis, early referral and effective immediate management in a centre with comprehensive provision and a multi-discipline approach. Specialist aftercare is also required. There is also a cohort of patients who have a congenital form of the disease who require ongoing apheresis (where a patient’s blood is filtered and then put back into their body). The national prevalence is 330 patients in England, with an acute incidence of 150 patients.
There is a very high mortality rate for patients with this disease: if a patient is treated outside of a specialist centre, the death rate is 50%. There are currently 2 centres in England where there are recognised services and where the survival rate is 80%.
NHS Arden & Greater East Midlands Commissioning Support Unit (AGCSU) on behalf of the Commissioner(s), NHS England - Specialised Commissioning, are looking to commission up to a further 8 Centres across England for TTP services and are inviting interested Providers to register their interest for these services. The service is a Schedule 3 Service and is being procured under the Light Touch Regime (LTR) of the Public Contract Regulations 2015.
There are patient flows to London from all over the South East. Commissioners have considered establishing one specialist provider for all of London and the South East and this is the default commissioner position.
Commissioners will consider bids for the South East (Thames Valley and Hampshire and Isle of Wight areas - (Lot 2)), to facilitate patient choice and to reduce the requirement to travel for providers who meet the criteria in the service specification, in the technical questionnaire and who are willing to work within a Clinical Partnership with the successful bidder for the London and South East Lot (Lot 1).
The contracting term for these services will be for a period of up to 4 years. Providers will need to register for the Provider Selection Process which is due to be published Mid-April / early May 2021.
two.2) Description
two.2.1) Title
Thrombotic Thrombocytopenic Purpura (TTP) - South East (Thames Valley, Hampshire and the Isle of Wight)
Lot No
2
two.2.2) Additional CPV code(s)
- 85000000 - Health and social work services
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKJ - South East (England)
Main site or place of performance
South East (Thames Valley, Hampshire and the Isle of Wight)
two.2.4) Description of the procurement
Thrombotic Thrombocytopenic Purpura (TTP) is a very rare, complex condition which can present as an acute life-threatening disorder that requires prompt diagnosis, early referral and effective immediate management in a centre with comprehensive provision and a multi-discipline approach. Specialist aftercare is also required. There is also a cohort of patients who have a congenital form of the disease who require ongoing apheresis (where a patient’s blood is filtered and then put back into their body). The national prevalence is 330 patients in England, with an acute incidence of 150 patients.
There is a very high mortality rate for patients with this disease: if a patient is treated outside of a specialist centre, the death rate is 50%. There are currently 2 centres in England where there are recognised services and where the survival rate is 80%.
NHS Arden & Greater East Midlands Commissioning Support Unit (AGCSU) on behalf of the Commissioner(s), NHS England - Specialised Commissioning, are looking to commission up to a further 8 Centres across England for TTP services and are inviting interested Providers to register their interest for these services. The service is a Schedule 3 Service and is being procured under the Light Touch Regime (LTR) of the Public Contract Regulations 2015.
The contracting term for these services will be for a period of up to 4 years. Providers will need to register for the Provider Selection Process which is due to be published Mid-April / early May 2021.
two.2) Description
two.2.1) Title
Thrombotic Thrombocytopenic Purpura (TTP) - South West
Lot No
3
two.2.2) Additional CPV code(s)
- 85000000 - Health and social work services
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKK - South West (England)
Main site or place of performance
South West
two.2.4) Description of the procurement
Thrombotic Thrombocytopenic Purpura (TTP) is a very rare, complex condition which can present as an acute life-threatening disorder that requires prompt diagnosis, early referral and effective immediate management in a centre with comprehensive provision and a multi-discipline approach. Specialist aftercare is also required. There is also a cohort of patients who have a congenital form of the disease who require ongoing apheresis (where a patient’s blood is filtered and then put back into their body). The national prevalence is 330 patients in England, with an acute incidence of 150 patients.
There is a very high mortality rate for patients with this disease: if a patient is treated outside of a specialist centre, the death rate is 50%. There are currently 2 centres in England where there are recognised services and where the survival rate is 80%.
NHS Arden & Greater East Midlands Commissioning Support Unit (AGCSU) on behalf of the Commissioner(s), NHS England - Specialised Commissioning, are looking to commission up to a further 8 Centres across England for TTP services and are inviting interested Providers to register their interest for these services. The service is a Schedule 3 Service and is being procured under the Light Touch Regime (LTR) of the Public Contract Regulations 2015.
The contracting term for these services will be for a period of up to 4 years. Providers will need to register for the Provider Selection Process which is due to be published Mid-April / early May 2021.
two.2) Description
two.2.1) Title
Thrombotic Thrombocytopenic Purpura (TTP) - West Midlands
Lot No
4
two.2.2) Additional CPV code(s)
- 85000000 - Health and social work services
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKG - West Midlands (England)
Main site or place of performance
West Midlands
two.2.4) Description of the procurement
Thrombotic Thrombocytopenic Purpura (TTP) is a very rare, complex condition which can present as an acute life-threatening disorder that requires prompt diagnosis, early referral and effective immediate management in a centre with comprehensive provision and a multi-discipline approach. Specialist aftercare is also required. There is also a cohort of patients who have a congenital form of the disease who require ongoing apheresis (where a patient’s blood is filtered and then put back into their body). The national prevalence is 330 patients in England, with an acute incidence of 150 patients.
There is a very high mortality rate for patients with this disease: if a patient is treated outside of a specialist centre, the death rate is 50%. There are currently 2 centres in England where there are recognised services and where the survival rate is 80%.
NHS Arden & Greater East Midlands Commissioning Support Unit (AGCSU) on behalf of the Commissioner(s), NHS England - Specialised Commissioning, are looking to commission up to a further 8 Centres across England for TTP services and are inviting interested Providers to register their interest for these services. The service is a Schedule 3 Service and is being procured under the Light Touch Regime (LTR) of the Public Contract Regulations 2015.
The contracting term for these services will be for a period of up to 4 years. Providers will need to register for the Provider Selection Process which is due to be published Mid-April / early May 2021.
two.2) Description
two.2.1) Title
Thrombotic Thrombocytopenic Purpura (TTP) - East Midlands
Lot No
5
two.2.2) Additional CPV code(s)
- 85000000 - Health and social work services
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKF - East Midlands (England)
Main site or place of performance
East Midlands
two.2.4) Description of the procurement
Thrombotic Thrombocytopenic Purpura (TTP) is a very rare, complex condition which can present as an acute life-threatening disorder that requires prompt diagnosis, early referral and effective immediate management in a centre with comprehensive provision and a multi-discipline approach. Specialist aftercare is also required. There is also a cohort of patients who have a congenital form of the disease who require ongoing apheresis (where a patient’s blood is filtered and then put back into their body). The national prevalence is 330 patients in England, with an acute incidence of 150 patients.
There is a very high mortality rate for patients with this disease: if a patient is treated outside of a specialist centre, the death rate is 50%. There are currently 2 centres centre in England where there are recognised services and where the survival rate is 80%.
NHS Arden & Greater East Midlands Commissioning Support Unit (AGCSU) on behalf of the Commissioner(s), NHS England - Specialised Commissioning, are looking to commission up to a further 8 Centres across England for TTP services and are inviting interested Providers to register their interest for these services. The service is a Schedule 3 Service and is being procured under the Light Touch Regime (LTR) of the Public Contract Regulations 2015.
The contracting term for these services will be for a period of up to 4 years. Providers will need to register for the Provider Selection Process which is due to be published Mid-April / early May 2021.
two.2) Description
two.2.1) Title
Thrombotic Thrombocytopenic Purpura (TTP) - East of England
Lot No
6
two.2.2) Additional CPV code(s)
- 85000000 - Health and social work services
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKH - East of England
Main site or place of performance
East of England
two.2.4) Description of the procurement
Thrombotic Thrombocytopenic Purpura (TTP) is a very rare, complex condition which can present as an acute life-threatening disorder that requires prompt diagnosis, early referral and effective immediate management in a centre with comprehensive provision and a multi-discipline approach. Specialist aftercare is also required. There is also a cohort of patients who have a congenital form of the disease who require ongoing apheresis (where a patient’s blood is filtered and then put back into their body). The national prevalence is 330 patients in England, with an acute incidence of 150 patients.
There is a very high mortality rate for patients with this disease: if a patient is treated outside of a specialist centre, the death rate is 50%. There are currently 2 centres in England where there are recognised services and where the survival rate is 80%.
NHS Arden & Greater East Midlands Commissioning Support Unit (AGCSU) on behalf of the Commissioner(s), NHS England - Specialised Commissioning, are looking to commission up to a further 8 Centres across England for TTP services and are inviting interested Providers to register their interest for these services. The service is a Schedule 3 Service and is being procured under the Light Touch Regime (LTR) of the Public Contract Regulations 2015.
The contracting term for these services will be for a period of up to 4 years. Providers will need to register for the Provider Selection Process which is due to be published Mid-April / early May 2021.
two.2) Description
two.2.1) Title
Thrombotic Thrombocytopenic Purpura (TTP) - North East
Lot No
7
two.2.2) Additional CPV code(s)
- 85000000 - Health and social work services
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKC - North East (England)
Main site or place of performance
North East
two.2.4) Description of the procurement
Thrombotic Thrombocytopenic Purpura (TTP) is a very rare, complex condition which can present as an acute life-threatening disorder that requires prompt diagnosis, early referral and effective immediate management in a centre with comprehensive provision and a multi-discipline approach. Specialist aftercare is also required. There is also a cohort of patients who have a congenital form of the disease who require ongoing apheresis (where a patient’s blood is filtered and then put back into their body). The national prevalence is 330 patients in England, with an acute incidence of 150 patients.
There is a very high mortality rate for patients with this disease: if a patient is treated outside of a specialist centre, the death rate is 50%. There are currently 2 centres in England where there are recognised services and where the survival rate is 80%.
NHS Arden & Greater East Midlands Commissioning Support Unit (AGCSU) on behalf of the Commissioner(s), NHS England - Specialised Commissioning, are looking to commission up to a further 8 Centres across England for TTP services and are inviting interested Providers to register their interest for these services. The service is a Schedule 3 Service and is being procured under the Light Touch Regime (LTR) of the Public Contract Regulations 2015.
The contracting term for these services will be for a period of up to 4 years. Providers will need to register for the Provider Selection Process which is due to be published Mid-April / early May 2021.
two.2) Description
two.2.1) Title
Thrombotic Thrombocytopenic Purpura (TTP) - Yorkshire and the Humber
Lot No
8
two.2.2) Additional CPV code(s)
- 85000000 - Health and social work services
- 85100000 - Health services
two.2.3) Place of performance
NUTS codes
- UKE - Yorkshire and the Humber
Main site or place of performance
Yorkshire and the Humber
two.2.4) Description of the procurement
Thrombotic Thrombocytopenic Purpura (TTP) is a very rare, complex condition which can present as an acute life-threatening disorder that requires prompt diagnosis, early referral and effective immediate management in a centre with comprehensive provision and a multi-discipline approach. Specialist aftercare is also required. There is also a cohort of patients who have a congenital form of the disease who require ongoing apheresis (where a patient’s blood is filtered and then put back into their body). The national prevalence is 330 patients in England, with an acute incidence of 150 patients.
There is a very high mortality rate for patients with this disease: if a patient is treated outside of a specialist centre, the death rate is 50%. There are currently 2 centres in England where there are recognised services and where the survival rate is 80%.
NHS Arden & Greater East Midlands Commissioning Support Unit (AGCSU) on behalf of the Commissioner(s), NHS England - Specialised Commissioning, are looking to commission up to a further 8 Centres across England for TTP services and are inviting interested Providers to register their interest for these services. The service is a Schedule 3 Service and is being procured under the Light Touch Regime (LTR) of the Public Contract Regulations 2015.
The contracting term for these services will be for a period of up to 4 years. Providers will need to register for the Provider Selection Process which is due to be published Mid-April / early May 2021.
two.3) Estimated date of publication of contract notice
4 May 2021
Section six. Complementary information
six.3) Additional information
In response to a recommendation from the Prescribed Specialised Services Advisory Group in 2014, NHS England developed a service model that aimed to balance the high levels of multi-disciplinary expertise required to treat patients with TTP with the requirement for patients to be treated rapidly to have optimal outcomes. NHS England undertook a public consultation on the draft service specification, which closed in October 2018. The consultation documents are still available on the NHS England website at this link:
Consultation on service specifications for thrombotic thrombocytopenic purpura (TTP) for all ages - NHS England - Citizen Space.
The model of delivery is to offer in-patient care within a specialist TTP centre, Patients with TTP require lifelong monitoring and follow up to manage relapse. Shared care is possible, based on the preference of the patient. Specialist TTP centres are required to undertake a clinical leadership, proactive education and outreach service to hospitals within their region to improve the identification of patients with TTP and the timely referral of patients to the specialist TTP centres.
Specialist TTP centres are required to establish robust clinical partnerships with paediatric haematology centres to provide support in relation to the treatment of children and to agree a transition policy.
There are patient flows to London from all over the South East. Commissioners have considered establishing one provider for all of London and the South East and this is the default Commissioner position.
Commissioners will consider bids for the South East (Thames Valley and Hampshire and Isle of Wight areas, (Lot 2)) to facilitate patient choice and to reduce the requirement to travel for providers who meet the criteria in the service specification, in the technical questionnaire and who are willing to work within a Clinical Partnership with the successful bidder for the London and South East Lot (Lot 1).
This will support effective care and improve local patient access to the service whilst ensuring availability of clinical expertise as appropriate.
Commissioners are planning to publish the Provider Selection process Mid-April / early May 2021. To register your interest in these services please follow this link https://uk.eu-supply.com/ctm/supplier/publictenders?B=UK and either login or register on EU Supply and search from ID number 44013.