Contract

(NU/1818) The Supply and Installation of a Multiplexed Platform for Measuring Protein Biomarkers with Spatial Resolution at Single Cell Scale

  • Newcastle University

F03: Contract award notice

Notice identifier: 2023/S 000-005782

Procurement identifier (OCID): ocds-h6vhtk-03754a

Published 28 February 2023, 10:53am



Section one: Contracting authority

one.1) Name and addresses

Newcastle University

Newcastle University, Procurement Services, Kingsgate

Newcastle

NE1 7RU

Contact

Dr Emma Barksby

Email

emma.barksby@ncl.ac.uk

Telephone

+44 1912086298

Country

United Kingdom

Region code

UKC22 - Tyneside

Internet address(es)

Main address

https://www.ncl.ac.uk

Buyer's address

https://www.ncl.ac.uk

one.4) Type of the contracting authority

Body governed by public law

one.5) Main activity

Education


Section two: Object

two.1) Scope of the procurement

two.1.1) Title

(NU/1818) The Supply and Installation of a Multiplexed Platform for Measuring Protein Biomarkers with Spatial Resolution at Single Cell Scale

Reference number

DN637330

two.1.2) Main CPV code

  • 38000000 - Laboratory, optical and precision equipments (excl. glasses)

two.1.3) Type of contract

Supplies

two.1.4) Short description

Newcastle University conducts significant discovery and clinical research on human tissue (healthy and diseased) as well as tissues from other relevant biological models. As part of an MRC equipment award (potential), the University are seeking to purchase a technology that can measure multiple protein biomarkers on various tissues and cellular samples with single cell spatial resolution. Due to the sheer nature and complexity of the biological/clinical questions, the system must be able to detect a minimum of 150 protein biomarkers on the same tissue/cell sample. Such a platform will underpin existing work by the FMS core technology platforms including flow cytometry, Bio-imaging and single cell technologies.

This tender process is for an analysis platform that is able to detect and measure over 100 protein biomarkers with single-cell level spatial and morphometric resolution in various tissue sections (fixed/frozen and formalin-fixed paraffin embedded – FFPE- samples) as well as immobilised suspension/adherent primary cells and cell lines. The platform should be easy to use with set up and walk away features and be able to utilise a range of freely available reagents from various competitive suppliers. It should also be able to be operated in a high-throughput manner with options for multi-slide loading and automated staining/imaging as one unit. The system must also come with dedicated data analysis options to include single cell segmentation, phenotypic exploration, and spatial mapping. The system will be operated and supported by the Newcastle Flow Cytometry and Single cell analysis core facility team as a collaboration with the Bio-Imaging Unit. As part of the offer, we are seeking on-site training for a minimum of three people in all aspects of the platform’s operation, including any associated data analysis packages. The offer must include the specified warranty, service and maintenance cover specified in Section 3.2. Please note that the University reserves the right not to make an award of contract.

two.1.6) Information about lots

This contract is divided into lots: No

two.1.7) Total value of the procurement (excluding VAT)

Lowest offer: £400,000 / Highest offer: £500,000 taken into consideration

two.2) Description

two.2.2) Additional CPV code(s)

  • 51430000 - Installation services of laboratory equipment

two.2.3) Place of performance

NUTS codes
  • UKC22 - Tyneside

two.2.4) Description of the procurement

This tender process is for an analysis platform that is able to detect and measure over 100 protein biomarkers with single-cell level spatial and morphometric resolution in various tissue sections (fixed/frozen and formalin-fixed paraffin embedded – FFPE- samples) as well as immobilised suspension/adherent primary cells and cell lines. The platform should be easy to use with set up and walk away features and be able to utilise a range of freely available reagents from various competitive suppliers. It should also be able to be operated in a high-throughput manner with options for multi-slide loading and automated staining/imaging as one unit. The system must also come with dedicated data analysis options to include single cell segmentation, phenotypic exploration, and spatial mapping. The system will be operated and supported by the Newcastle Flow Cytometry and Single cell analysis core facility team as a collaboration with the Bio-Imaging Unit. As part of the offer, we are seeking on-site training for a minimum of three people in all aspects of the platform’s operation, including any associated data analysis packages. The offer must include the specified warranty, service and maintenance cover specified in Section 3.2. Please note that the University reserves the right not to make an award of contract.

two.2.5) Award criteria

Quality criterion - Name: Ability to Meet the Technical Specification / Weighting: 50

Quality criterion - Name: Quality of Delivery, Warranty, Servicing and Maintenance / Weighting: 20

Price - Weighting: 30

two.2.11) Information about options

Options: No

two.2.13) Information about European Union Funds

The procurement is related to a project and/or programme financed by European Union funds: No


Section four. Procedure

four.1) Description

four.1.1) Type of procedure

Open procedure

four.1.8) Information about the Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: Yes

four.2) Administrative information

four.2.1) Previous publication concerning this procedure

Notice number: 2022/S 000-028785


Section five. Award of contract

Contract No

NU/1818

A contract/lot is awarded: Yes

five.2) Award of contract

five.2.1) Date of conclusion of the contract

5 December 2022

five.2.2) Information about tenders

Number of tenders received: 2

Number of tenders received from SMEs: 0

Number of tenders received from tenderers from other EU Member States: 0

Number of tenders received from tenderers from non-EU Member States: 1

Number of tenders received by electronic means: 2

The contract has been awarded to a group of economic operators: No

five.2.3) Name and address of the contractor

Miltenyi Biotec Ltd

Almac House, Church Lane

Woking

GU24 9DR

Country

United Kingdom

NUTS code
  • UKJ2 - Surrey, East and West Sussex
The contractor is an SME

No

five.2.4) Information on value of contract/lot (excluding VAT)

Lowest offer: £400,000 / Highest offer: £500,000 taken into consideration


Section six. Complementary information

six.4) Procedures for review

six.4.1) Review body

Newcastle University

Newcastle upon Tyne

Country

United Kingdom

Internet address

https://www.ncl.ac.uk

six.4.3) Review procedure

Precise information on deadline(s) for review procedures

Newcastle University will incorporate a minimum 10 calendar day standstill period at the point information on the award of the contract is communicated to tenderers. This period allows unsuccessful tenderers to seek further debriefing before the contract is entered into. Applicants have 2 working days from notification of the award decision to request additional debriefing and that information has to be provided a minimum of 3 working days before expiry of the standstill period. Such additional information should be requested from the address referred to in part 1.1 above. If an appeal regarding the award of a contract has not been successfully resolved, the Public Contracts Regulations 2015 provide for aggrieved parties who have been harmed or are at risk of harm by a breach of the rules to take action in the High Court (England, Wales and Northern Ireland). Any such action must be brought promptly. Where a contract has not been entered into the Court may order the setting aside of the award decision or order the authority to amend any document and may award damages. If the contract has been entered into the Court may only award damages