Section one: Contracting authority/entity
one.1) Name and addresses
National Physical Laboratory
Hampton Road
Teddington
TW11 0LW
Telephone
+44 2089776731
Country
United Kingdom
Region code
UK - United Kingdom
National registration number
02937881
Internet address(es)
Main address
one.4) Type of the contracting authority
Body governed by public law
one.5) Main activity
Other activity
Research
Section two: Object
two.1) Scope of the procurement
two.1.1) Title
TIMSTOF Flex MALDI-2: A Quadrupole TOF instrument capable of rapid MALDI MS imaging with high spatial resolution, laser post-ionisation and ion mobility separation
two.1.2) Main CPV code
- 38000000 - Laboratory, optical and precision equipments (excl. glasses)
two.1.3) Type of contract
Supplies
two.1.4) Short description
Our large-scale mass spectrometry imaging (MSI) studies require high throughput, high spatial resolution MSI analysis of multiple tissue sections, on multiple slides. Currently, of commercially available MSI instruments, matrix assisted laser desorption ionisation (MALDI) provides the best combination of spatial resolution and throughput. Crucially, high sensitivity for both lipids and metabolites must also be achieved. MALDI-2 has recently been shown to provide unrivalled limit-of-detection for a range of lipid and metabolite classes at high spatial resolution. The Bruker timsTOF Flex MALDI-2 instrument is the only commercially available instrument to feature MALDI-2 post ionisation and 5µm pixel size MSI
two.1.6) Information about lots
This contract is divided into lots: No
two.1.7) Total value of the procurement (excluding VAT)
Value excluding VAT: £1,600,000
two.2) Description
two.2.3) Place of performance
NUTS codes
- UK - United Kingdom
Main site or place of performance
NPL Management Limited
two.2.4) Description of the procurement
Matrix assisted laser desorption ionisation (MALDI) provides the highest commercially available spatial resolution for high throughput multi-slide analysis of biological samples by MSI. Recent advances in laser post-ionisation, termed MALDI-2, have demonstrated significant improvement in limit-of-detection for a range of analyte classes. The timsToF Flex MALDI-2 microGRID instrument should feature a dual electrospray and MALDI MSI ion source. It should feature MALDI-2 laser post-ionisation functionality and 5 µm pixel size microGRID technology. It should provide 60,000 mass resolving power and scan rates of 20Hz. The instrument should also provide trapped ion mobility separation technology (TIMS) MSI functionality.
two.2.11) Information about options
Options: No
two.2.13) Information about European Union Funds
The procurement is related to a project and/or programme financed by European Union funds: No
Section four. Procedure
four.1) Description
four.1.1) Type of procedure
Award of a contract without prior publication of a call for competition in the cases listed below
- The procurement falls outside the scope of application of the regulations
Explanation:
The Bruker timsTOF Flex with MALDI-2 is the only commercially available instrument to provide MALDI-2 post ionisation withiwth high throughput imaging at 5 µm pixel size. Unique features of this instrument include:
1. MALDI MSI with MALDI-2 post-ionisation MSI
2. MALDI MSI 5 µm pixel size microGRID technology
3. Trapped ion mobility spectrometry with MALDI imaging and MALDI-2 post-ionisation
four.1.8) Information about the Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement: No
Section five. Award of contract/concession
Title
TIMSTOF Flex MALDI-2: A Quadrupole TOF instrument capable of rapid MALDI MS imaging with high spatial resolution, laser post-ionisation and ion mobility separation
A contract/lot is awarded: Yes
five.2) Award of contract/concession
five.2.1) Date of conclusion of the contract
20 February 2023
five.2.2) Information about tenders
The contract has been awarded to a group of economic operators: No
five.2.3) Name and address of the contractor/concessionaire
Bruker UK Ltd
Welland House, Torwood Close, Westwood Business Park
Coventry
CV4 8HX
Country
United Kingdom
NUTS code
- UK - United Kingdom
The contractor/concessionaire is an SME
No
five.2.4) Information on value of contract/lot/concession (excluding VAT)
Total value of the contract/lot/concession: £1,600,000
five.2.5) Information about subcontracting
The contract/lot/concession is likely to be subcontracted
Section six. Complementary information
six.4) Procedures for review
six.4.1) Review body
NPL Management Limited
Hampton Road
Teddington
TW11 0LW
Telephone
+44 2089773222
Country
United Kingdom