Award

Select Series MRT Desorption Electrospray Ionization (DESI) system for sample preparation free tissue mass spectrometry imaging with superior molecular class coverage.

  • National Physical Laboratory

F15: Voluntary ex ante transparency notice

Notice identifier: 2023/S 000-005059

Procurement identifier (OCID): ocds-h6vhtk-03a6ef

Published 20 February 2023, 3:31pm



Section one: Contracting authority/entity

one.1) Name and addresses

National Physical Laboratory

Hampton Road

Teddington

TW11 0LW

Email

mandy.morgan@npl.co.uk

Telephone

+44 2089436731

Country

United Kingdom

Region code

UK - United Kingdom

Internet address(es)

Main address

www.npl.co.uk

one.4) Type of the contracting authority

Body governed by public law

one.5) Main activity

Other activity

Research


Section two: Object

two.1) Scope of the procurement

two.1.1) Title

Select Series MRT Desorption Electrospray Ionization (DESI) system for sample preparation free tissue mass spectrometry imaging with superior molecular class coverage.

two.1.2) Main CPV code

  • 38000000 - Laboratory, optical and precision equipments (excl. glasses)

two.1.3) Type of contract

Supplies

two.1.4) Short description

Desorption electrospray ionisation mass spectrometry imaging (DESI MSI) provides excellent metabolic coverage and throughput with minimal sample preparation for tissue imaging in pre-clinical and clinical studies. Waters produce the only commercially available DESI MSI system. This latest innovation (Select Series MRT with DESI XS source) builds substantially on their previous DESI systems enabling superior image resolution, useability, reliability, mass accuracy < 1ppm and mass resolving power of > 200,000 at scan rates of 10Hz.

two.1.6) Information about lots

This contract is divided into lots: No

two.1.7) Total value of the procurement (excluding VAT)

Value excluding VAT: £868,170.40

two.2) Description

two.2.3) Place of performance

NUTS codes
  • UK - United Kingdom

two.2.4) Description of the procurement

Our research in evaluation of multiple mass spectrometry imaging modalities shows that DESI provides a uniquely powerful combination of minimal sample preparation, low limits-of-detection and broad metabolic coverage. The Select Series MRT folded time of flight instrument should be equipped with the DESI XS ion source including motorised sample analysis stage, sample view camera and heated inlet capillary. It should provide DESI MSI functionality whilst offering >200,000 mass resolving power, < 1ppm mass accuracy, all at 10 Hz scan speeds. A range of pixel sizes and image ROIs should be available such that data acquisition at >10 µm pixel size over a full microscope slide comprised of multiple image regions area if desired. The DESI inlet capillary should have temperature controlled to enable optimisation of ionisation / transmission for different analyte classes. The solvent delivery for DESI sprayer should be provided by a HPLC type pump system.

two.2.11) Information about options

Options: No

two.2.13) Information about European Union Funds

The procurement is related to a project and/or programme financed by European Union funds: No


Section four. Procedure

four.1) Description

four.1.1) Type of procedure

Award of a contract without prior publication of a call for competition in the cases listed below

  • The procurement falls outside the scope of application of the regulations

Explanation:

DESI MSI is only commercially available from Waters Ltd and coupled to their Select Series MRT folded time-of-flight instrument provides a powerful, high throughput, high sensitivity, high mass resolving power and high spatial resolution biological imaging system. Unique features of the Select Series MRT DESI instrument include:

1. Imaging of biomolecules from tissue by DESI MSI.

2. DESI MSI tissue analysis with mass resolving power of > 200,000 in the m/z range 50 – 1000

3. DESI MSI tissue analysis with mass accuracy < 1 ppm, > 200,000 mass resolving power at scan rates of 10 Hz

four.1.8) Information about the Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: No


Section five. Award of contract/concession

Title

Select Series MRT Desorption Electrospray Ionization (DESI) system for sample preparation free tissue mass spectrometry imaging with superior molecular class coverage.

A contract/lot is awarded: Yes

five.2) Award of contract/concession

five.2.1) Date of conclusion of the contract

20 February 2023

five.2.2) Information about tenders

The contract has been awarded to a group of economic operators: No

five.2.3) Name and address of the contractor/concessionaire

Waters Limited

Stamford Avenue, Altrincham Road

Wimslow

SK9 4AX

Country

United Kingdom

NUTS code
  • UK - United Kingdom
National registration number

2912366

The contractor/concessionaire is an SME

No

five.2.4) Information on value of contract/lot/concession (excluding VAT)

Total value of the contract/lot/concession: £868,170.40

five.2.5) Information about subcontracting

The contract/lot/concession is likely to be subcontracted


Section six. Complementary information

six.4) Procedures for review

six.4.1) Review body

NPL Management Limited

National Physical Laboratory

Teddington

TW11 0LW

Telephone

+44 2089773222

Country

United Kingdom