Future opportunity

Genotyping data and genetic risk score processing and delivery services

  • Our Future Health (Akeso Acting on behalf of)

F01: Prior information notice (prior information only)

Notice reference: 2021/S 000-028803

Published 18 November 2021, 12:32pm

Section one: Contracting authority

one.1) Name and addresses

Our Future Health (Akeso Acting on behalf of)



Lauren Clarke




+44 2030111381


United Kingdom

NUTS code

UK - United Kingdom

Internet address(es)

Main address


one.3) Communication

Additional information can be obtained from the above-mentioned address

one.4) Type of the contracting authority

Body governed by public law

one.5) Main activity

Other activity

Health Research and Development

Section two: Object

two.1) Scope of the procurement

two.1.1) Title

Genotyping data and genetic risk score processing and delivery services

two.1.2) Main CPV code

  • 72316000 - Data analysis services

two.1.3) Type of contract


two.1.4) Short description

Our Future Health is seeking to engage the market and gain feedback on viable solutions for processing genotyping data including quality control, ancestry and relatedness analysis, imputation of additional genotypes, and calculation and delivery of polygenic risk scores or other genetic prediction models including genetic counselling services.

two.1.6) Information about lots

This contract is divided into lots: No

two.2) Description

two.2.2) Additional CPV code(s)

  • 73110000 - Research services

two.2.3) Place of performance

NUTS codes
  • UK - United Kingdom
  • AT - Austria
  • BE - Belgium
  • CH - Switzerland
  • DE - Germany
  • DK - Denmark
  • EE - Estonia
  • ES - Spain
  • FI - Finland
  • FR - France
  • IE - Ireland
  • IS - Iceland
  • IT - Italy
  • LU - Luxembourg
  • NL - Netherlands
  • NO - Norway
  • PT - Portugal
  • SE - Sweden
  • AU - Australia
  • CA - Canada
  • CL - Chile
  • IL - Israel
  • JP - Japan
  • KR - South Korea
  • NZ - New Zealand
  • TW - Taiwan
  • US - United States
  • UY - Uruguay

two.2.4) Description of the procurement

Our Future Health will be the UK's largest ever health research programme, aiming to build a cohort of five million people from all backgrounds and from right across the UK. Participants will be asked to complete an online questionnaire about their lifestyle and medical history and to provide a blood sample, from which DNA will be extracted and used to obtain genetic data.

Our Future Health will ask for permission to combine the information and samples provided with existing information about them, including their health records. Adding these additional types of information will help to build a more comprehensive picture of health and wellbeing that could be relevant to understanding what changes people's risk of disease. Combining these multiple sources of health and health-relevant information, including genetic data, will create an incredibly detailed picture that represents the whole of the UK. Researchers will use this information to make new discoveries about human health and diseases.

Our Future Health will use the health information, including genetic data, to calculate disease risk scores for its participants. Based on these risk profiles, it might be possible to better identify individuals who are at higher risk of developing certain diseases. This will provide an opportunity to test the potential of new diagnostic tests or treatments as they are discovered and to see how effective they could be for people at higher risk of certain diseases. This will also mean Our Future Health can facilitate research addressing important questions about the potential uses of genetic risk scores in health care.

Our Future Health expects genetic data to become available from mid-2022 and is now seeking to engage market providers of bioinformatics services to define requirements and capabilities relating to:

A scalable pipeline for genotyping data management, including individual, variant and batch quality control, and basic ancestry and relatedness analysis

- Robust and scalable imputation of additional variants using UK-wide reference panels with diverse ancestry

- Calculation of genetic risk scores (polygenic risk scores)

- Risk communication tools suitable for delivery of genetic risk score results to participants

- Genetic counselling or educational or other services suitable to support participants' informed decision-making regarding genetic information

- Calculation and presentation of genetic ancestry

Our Future Health are reviewing potential lot structures for this procurement and will be seeking feedback during the market engagement process.

two.2.14) Additional information

Providers in this market are invited to express interest in this procurement activity by email to ourfuturehealth@akesoco.com by Wednesday 1st December 2021. On receipt of expression of interest, providers will be asked to respond to a short questionnaire to gather information on optimal solutions for the service in advance of being invited to a briefing session on 8th December at 15:00-16:00 GMT, to describe the requirement and expectation of the service of the market in more detail.

two.3) Estimated date of publication of contract notice

14 February 2022

Section four. Procedure

four.1) Description

four.1.8) Information about the Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: Yes

Section six. Complementary information

six.3) Additional information

Supplier Engagement will be held in accordance with Regulation 40 & 41 of the Public

Contract Regulations 2015.

Please direct any enquiries about the procurement or business through Akeso and Co at the

above email address. No direct contact should be made with Our Future Health.